onr:"swepub:oai:DiVA.org:su-216296"
Search: onr:"swepub:oai:DiVA.org:su-216296" > MicroRNAs are deepl...
- 1 of 1
- Previous record
- Next record
- To hitlist
MicroRNAs are deeply linked to the emergence of the complex octopus brain
- Zolotarov, Grygoriy (author)
-
- Fromm, Bastian (author)
- Stockholms universitet,Institutionen för molekylär biovetenskap, Wenner-Grens institut,Science for Life Laboratory (SciLifeLab),UiT The Arctic University of Norway, Norway
- Legnini, Ivano (author)
- show more...
- Ayoub, Salah (author)
- Polese, Gianluca (author)
- Maselli, Valeria (author)
- Chabot, Peter J. (author)
- Vinther, Jakob (author)
- Styfhals, Ruth (author)
- Seuntjens, Eve (author)
- Di Cosmo, Anna (author)
- Peterson, Kevin J. (author)
- Rajewsky, Nikolaus (author)
- show less...
- (creator_code:org_t)
- American Association for the Advancement of Science (AAAS), 2022
- 2022
- English.
- In: Science Advances. - : American Association for the Advancement of Science (AAAS). - 2375-2548. ; 8:47
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- Soft-bodied cephalopods such as octopuses are exceptionally intelligent invertebrates with a highly complex nervous system that evolved independently from vertebrates. Because of elevated RNA editing in their nervous tissues, we hypothesized that RNA regulation may play a major role in the cognitive success of this group. We thus profiled messenger RNAs and small RNAs in three cephalopod species including 18 tissues of the Octopus vulgaris. We show that the major RNA innovation of soft-bodied cephalopods is an expansion of the microRNA (miRNA) gene repertoire. These evolutionarily novel miRNAs were primarily expressed in adult neuronal tissues and during the development and had conserved and thus likely functional target sites. The only comparable miRNA expansions happened, notably, in vertebrates. Thus, we propose that miRNAs are intimately linked to the evolution of complex animal brains.
Subject headings
- NATURVETENSKAP -- Biologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Science Advances (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Zolotarov, Grygo ...
- Fromm, Bastian
- Legnini, Ivano
- Ayoub, Salah
- Polese, Gianluca
- Maselli, Valeria
- show more...
- Chabot, Peter J.
- Vinther, Jakob
- Styfhals, Ruth
- Seuntjens, Eve
- Di Cosmo, Anna
- Peterson, Kevin ...
- Rajewsky, Nikola ...
- show less...
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Biological Scien ...
- Articles in the publication
- Science Advances
- By the university
- Stockholm University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
