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Recent developments in frailty identification, management, risk factors and prevention : A narrative review of leading journals in geriatrics and gerontology

Dent, Elsa (author)
Hanlon, Peter (author)
Sim, Marc (author)
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Jylhävä, Juulia (author)
Liu, Zuyun (author)
Vetrano, Davide L. (author)
Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Stockholm Gerontology Research Center, Sweden
Stolz, Erwin (author)
Pérez-Zepeda, Mario Ulises (author)
Crabtree, Daniel R. (author)
Nicholson, Caroline (author)
Job, Jenny (author)
Ambagtsheer, Rachel C. (author)
Ward, Paul R. (author)
Shi, Sandra M. (author)
Huynh, Quan (author)
Hoogendijk, Emiel O. (author)
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 (creator_code:org_t)
2023
2023
English.
In: Ageing Research Reviews. - 1568-1637 .- 1872-9649. ; 91
  • Research review (peer-reviewed)
Abstract Subject headings
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  • Frailty is an age-related clinical condition characterised by an increased susceptibility to stressors and an elevated risk of adverse outcomes such as mortality. In the light of global population ageing, the prevalence of frailty is expected to soar in coming decades. This narrative review provides critical insights into recent developments and emerging practices in frailty research regarding identification, management, risk factors, and prevention. We searched journals in the top two quartiles of geriatrics and gerontology (from Clarivate Journal Citation Reports) for articles published between 01 January 2018 and 20 December 2022. Several recent developments were identified, including new biomarkers and biomarker panels for frailty screening and diagnosis, using artificial intelligence to identify frailty, and investigating the altered response to medications by older adults with frailty. Other areas with novel developments included exercise (including technology-based exercise), multidimensional interventions, person-centred and integrated care, assistive technologies, analysis of frailty transitions, risk-factors, clinical guidelines, COVID-19, and potential future treatments. This review identified a strong need for the implementation and evaluation of cost-effective, community-based interventions to manage and prevent frailty. Our findings highlight the need to better identify and support older adults with frailty and involve those with frailty in shared decision-making regarding their care.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)

Keyword

Aged
Biomarkers
Frailty
Geriatric Assessment
Risk Factors

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