onr:"swepub:oai:DiVA.org:su-25185"
Search: onr:"swepub:oai:DiVA.org:su-25185" > Maternal country of...
- 1 of 1
- Previous record
- Next record
- To hitlist
- Amoudruz, PetraStockholms universitet,Wenner-Grens institut (author)
Maternal country of birth and previous pregnancies are associated with breast milk characteristics
- Article/chapterEnglish2009
Publisher, publication year, extent ...
- Wiley,2009
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:su-25185
- https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-25185URI
- https://doi.org/10.1111/j.1399-3038.2008.00754.xDOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-3764URI
- http://kipublications.ki.se/Default.aspx?queryparsed=id:118161236URI
Supplementary language notes
- Language:English
- Summary in:English
Part of subdatabase
- SwePubSwePub
Classification
Notes
- Populations in high infectious exposure countries are at low risk of some immune-mediated diseases such as Crohn’s disease and allergy. This low risk is maintained upon immigration to an industrialized country, but the offspring of such immigrants have a higher immune-mediated disease risk than the indigenous population. We hypothesize that early life exposures in a developing country shape the maternal immune system, which could have implications for the offspring born in a developed country with a low infectious load. The aim of this study was to investigate if exposures in childhood (indicated by country of origin) and subsequent exposures influence immunologic characteristics relevant to stimulation of offspring. Breast milk components among 64 mothers resident in Sweden, 32 of whom immigrated from a developing country, were examined using the ELISA and Cytometric Bead Array methods. Immigrants from a developing country had statistically significantly higher levels of breast milk interleukin-6 (IL-6), IL-8 and transforming growth factor-β1. A larger number of previous pregnancies were associated with down-regulation of several substances, statistically significant for soluble CD14 and IL-8. The results suggest that maternal country of birth may influence adult immune characteristics, potentially relevant to disease risk in offspring. Such a mechanism may explain the higher immune-mediated disease risk among children of migrants from a developing to developed country. Older siblings may influence disease risk through the action of previous pregnancies on maternal immune characteristics.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Pediatrik hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Pediatrics hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Mikrobiologi inom det medicinska området hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Microbiology in the medical area hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Immunologi inom det medicinska området hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Immunology in the medical area hsv//eng
- allergy
- breast milk
- cytometric bead array
- cytokines;exposures
- inflammatory bowel disease
- immigrants
- lipopolysaccharide
- soluble CD14
- siblings
- Paediatric medicine
- Pediatrisk medicin
- MEDICINE
- Microbiology, immunology, infectious diseases
- Immunology
- Immunologi
Added entries (persons, corporate bodies, meetings, titles ...)
- Holmlund, UlrikaStockholms universitet,Wenner-Grens institut(Swepub:su)ulho0917 (author)
- Schollin, JensÖrebro universitet,Hälsoakademin(Swepub:oru)jssn (author)
- Sverremark-Ekström, EvaStockholms universitet,Wenner-Grens institut(Swepub:su)esver (author)
- Montgomery, Scott MKarolinska Institutet,Örebro universitet,Stockholms universitet,Psykologiska institutionen,Hälsoakademin(Swepub:oru)smy (author)
- Stockholms universitetWenner-Grens institut (creator_code:org_t)
Related titles
- In:Pediatric Allergy and Immunology: Wiley20:1, s. 19-290905-61571399-3038
Internet link
- https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1399-3038.2008.00754.x
- https://doi.org/10.1111/j.1399-3038.2008.00754.xFulltext
- https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-25185
- https://doi.org/10.1111/j.1399-3038.2008.00754.x
- https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-3764
- http://kipublications.ki.se/Default.aspx?queryparsed=id:118161236
Find in a library
- Pediatric Allergy and Immunology (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Amoudruz, Petra
- Holmlund, Ulrika
- Schollin, Jens
- Sverremark-Ekstr ...
- Montgomery, Scot ...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Pediatrics
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Basic Medicine
- and Microbiology in ...
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Basic Medicine
- and Immunology in th ...
- Articles in the publication
- Pediatric Allerg ...
- By the university
- Stockholm University
- Örebro University
- Karolinska Institutet
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
