onr:"swepub:oai:DiVA.org:su-25185"
Sökning: onr:"swepub:oai:DiVA.org:su-25185" > Maternal country of...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 04956naa a2200649 4500 | |
| 001 | oai:DiVA.org:su-25185 | |
| 003 | SwePub | |
| 008 | 080520s2009 | |||||||||||000 ||eng| | |
| 009 | oai:DiVA.org:oru-3764 | |
| 009 | oai:prod.swepub.kib.ki.se:118161236 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-251852 URI |
| 024 | 7 | a https://doi.org/10.1111/j.1399-3038.2008.00754.x2 DOI |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-37642 URI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1181612362 URI |
| 040 | a (SwePub)sud (SwePub)orud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Amoudruz, Petrau Stockholms universitet,Wenner-Grens institut4 aut |
| 245 | 1 0 | a Maternal country of birth and previous pregnancies are associated with breast milk characteristics |
| 264 | 1 | b Wiley,c 2009 |
| 338 | a print2 rdacarrier | |
| 520 | a Populations in high infectious exposure countries are at low risk of some immune-mediated diseases such as Crohn’s disease and allergy. This low risk is maintained upon immigration to an industrialized country, but the offspring of such immigrants have a higher immune-mediated disease risk than the indigenous population. We hypothesize that early life exposures in a developing country shape the maternal immune system, which could have implications for the offspring born in a developed country with a low infectious load. The aim of this study was to investigate if exposures in childhood (indicated by country of origin) and subsequent exposures influence immunologic characteristics relevant to stimulation of offspring. Breast milk components among 64 mothers resident in Sweden, 32 of whom immigrated from a developing country, were examined using the ELISA and Cytometric Bead Array methods. Immigrants from a developing country had statistically significantly higher levels of breast milk interleukin-6 (IL-6), IL-8 and transforming growth factor-β1. A larger number of previous pregnancies were associated with down-regulation of several substances, statistically significant for soluble CD14 and IL-8. The results suggest that maternal country of birth may influence adult immune characteristics, potentially relevant to disease risk in offspring. Such a mechanism may explain the higher immune-mediated disease risk among children of migrants from a developing to developed country. Older siblings may influence disease risk through the action of previous pregnancies on maternal immune characteristics. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Pediatrik0 (SwePub)302212 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Pediatrics0 (SwePub)302212 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Mikrobiologi inom det medicinska området0 (SwePub)301092 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Microbiology in the medical area0 (SwePub)301092 hsv//eng |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Immunologi inom det medicinska området0 (SwePub)301102 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Immunology in the medical area0 (SwePub)301102 hsv//eng |
| 653 | a allergy | |
| 653 | a breast milk | |
| 653 | a cytometric bead array | |
| 653 | a cytokines;exposures | |
| 653 | a inflammatory bowel disease | |
| 653 | a immigrants | |
| 653 | a lipopolysaccharide | |
| 653 | a soluble CD14 | |
| 653 | a siblings | |
| 653 | a Paediatric medicine | |
| 653 | a Pediatrisk medicin | |
| 653 | a MEDICINE | |
| 653 | a Microbiology, immunology, infectious diseases | |
| 653 | a Immunology | |
| 653 | a Immunologi | |
| 700 | 1 | a Holmlund, Ulrikau Stockholms universitet,Wenner-Grens institut4 aut0 (Swepub:su)ulho0917 |
| 700 | 1 | a Schollin, Jensu Örebro universitet,Hälsoakademin4 aut0 (Swepub:oru)jssn |
| 700 | 1 | a Sverremark-Ekström, Evau Stockholms universitet,Wenner-Grens institut4 aut0 (Swepub:su)esver |
| 700 | 1 | a Montgomery, Scott Mu Karolinska Institutet,Örebro universitet,Stockholms universitet,Psykologiska institutionen,Hälsoakademin4 aut0 (Swepub:oru)smy |
| 710 | 2 | a Stockholms universitetb Wenner-Grens institut4 org |
| 773 | 0 | t Pediatric Allergy and Immunologyd : Wileyg 20:1, s. 19-29q 20:1<19-29x 0905-6157x 1399-3038 |
| 856 | 4 | u https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1399-3038.2008.00754.x |
| 856 | 4 | u https://doi.org/10.1111/j.1399-3038.2008.00754.xy Fulltext |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-25185 |
| 856 | 4 8 | u https://doi.org/10.1111/j.1399-3038.2008.00754.x |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-3764 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:118161236 |
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