onr:"swepub:oai:DiVA.org:su-76331"
Search: onr:"swepub:oai:DiVA.org:su-76331" > A flow-through pass...
- 1 of 1
- Previous record
- Next record
- To hitlist
A flow-through passive dosing system for continuously supplying aqueous solutions of hydrophobic chemicals to bioconcentration and aquatic toxicity tests
-
- Adolfsson-Erici, Margaretha (author)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
-
- Åkerman, Gun (author)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
-
- Jahnke, Annika (author)
- Stockholms universitet,Institutionen för tillämpad miljövetenskap (ITM)
- show more...
- Mayer, Philipp (author)
- show less...
- (creator_code:org_t)
- Elsevier BV, 2012
- 2012
- English.
- In: Chemosphere. - : Elsevier BV. - 0045-6535 .- 1879-1298. ; 86:6, s. 593-599
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- A continuous supply of water with defined stable concentrations of hydrophobic chemicals is a requirement in a range of laboratory tests such as the OECD 305 protocol for determining the bioconcentration factor in fish. Satisfying this requirement continues to be a challenge, particularly for hydrophobic chemicals. Here we present a novel solution based on equilibrium passive dosing. It employs a commercially available unit consisting of similar to 16000 polydimethylsiloxane (PDMS) tubes connected to two manifolds. The chemicals are loaded into the unit by repeatedly perfusing it with a methanol solution of the substances that is progressively diluted with water. Thereafter the unit is perfused with water and the chemicals partition from the unit into the water. The system was tested with nine chemicals with logK(ow) ranging from 4.1 to 6.3. The aqueous concentrations generated were shown to be largely independent of the water flow rate, and the unit to unit reproducibility was within a factor of similar to 2. In continuous flow experiments the aqueous concentrations of most of the study chemicals remained constant over 8 d. A model was assembled that allows prediction of the operating characteristics of the system from the logKow or PDMS/water partition coefficient of the chemical. The system is a simple, safe, predictable and flexible tool that generates stable aqueous concentrations of hydrophobic chemicals.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
Keyword
- Passive dosing
- Contaminant dosing
- PDMS
- Constant water concentrations
- Bioconcentration test
- OECD 305
Publication and Content Type
- ref (subject category)
- art (subject category)
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Adolfsson-Erici, ...
- Åkerman, Gun
- Jahnke, Annika
- Mayer, Philipp
- McLachlan, Micha ...
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Earth and Relate ...
- and Environmental Sc ...
- Articles in the publication
- Chemosphere
- By the university
- Stockholm University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
