Search: onr:"swepub:oai:DiVA.org:su-76769" >
The Pfam protein fa...
The Pfam protein families database
-
Punta, Marco (author)
-
Coggill, Penny C. (author)
-
Eberhardt, Ruth Y. (author)
-
show more...
-
Mistry, Jaina (author)
-
Tate, John (author)
-
Boursnell, Chris (author)
-
Pang, Ningze (author)
-
- Forslund, Kristoffer (author)
- Stockholms universitet,Institutionen för biokemi och biofysik,Science for Life Laboratory (SciLifeLab)
-
Ceric, Goran (author)
-
Clements, Jody (author)
-
Heger, Andreas (author)
-
Holm, Liisa (author)
-
- Sonnhammer, Erik L. L. (author)
- Stockholms universitet,Institutionen för biokemi och biofysik,Science for Life Laboratory (SciLifeLab)
-
Eddy, Sean R. (author)
-
Bateman, Alex (author)
-
Finn, Robert D. (author)
-
show less...
-
(creator_code:org_t)
- 2011-11-29
- 2012
- English.
-
In: Nucleic Acids Research. - : Oxford University Press (OUP). - 0305-1048 .- 1362-4962. ; 40:D1, s. D290-D301
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://academic.oup...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Pfam is a widely used database of protein families, currently containing more than 13 000 manually curated protein families as of release 26.0. Pfam is available via servers in the UK (http://pfam.sanger.ac.uk/), the USA (http://pfam.janelia.org/) and Sweden (http://pfam.sbc.su.se/). Here, we report on changes that have occurred since our 2010 NAR paper (release 24.0). Over the last 2 years, we have generated 1840 new families and increased coverage of the UniProt Knowledgebase (UniProtKB) to nearly 80%. Notably, we have taken the step of opening up the annotation of our families to the Wikipedia community, by linking Pfam families to relevant Wikipedia pages and encouraging the Pfam and Wikipedia communities to improve and expand those pages. We continue to improve the Pfam website and add new visualizations, such as the 'sunburst' representation of taxonomic distribution of families. In this work we additionally address two topics that will be of particular interest to the Pfam community. First, we explain the definition and use of family-specific, manually curated gathering thresholds. Second, we discuss some of the features of domains of unknown function (also known as DUFs), which constitute a rapidly growing class of families within Pfam.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biofysik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biophysics (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Punta, Marco
-
Coggill, Penny C ...
-
Eberhardt, Ruth ...
-
Mistry, Jaina
-
Tate, John
-
Boursnell, Chris
-
show more...
-
Pang, Ningze
-
Forslund, Kristo ...
-
Ceric, Goran
-
Clements, Jody
-
Heger, Andreas
-
Holm, Liisa
-
Sonnhammer, Erik ...
-
Eddy, Sean R.
-
Bateman, Alex
-
Finn, Robert D.
-
show less...
- About the subject
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Biochemistry and ...
-
- NATURAL SCIENCES
-
NATURAL SCIENCES
-
and Biological Scien ...
-
and Biophysics
- Articles in the publication
-
Nucleic Acids Re ...
- By the university
-
Stockholm University