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Midlife healthy-die...
Midlife healthy-diet index and late-life dementia and Alzheimer's disease
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- Eskelinen, Marjo H (author)
- Department of Neurology, University of Eastern Finland, Kuopio
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- Ngandu, Tiia (author)
- Karolinska Institutet
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- Tuomilehto, Jaakko (author)
- Department of Health Promotion and Chronic Disease Prevention, National Institute for Health and Welfare
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- Soininen, Hilkka (author)
- Department of Neurology, University of Eastern Finland, Kuopio
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- Kivipelto, Miia (author)
- Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI)
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(creator_code:org_t)
- 2011-04-27
- 2011
- English.
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In: Dementia and Geriatric Cognitive Disorders Extra. - Basel : S. Karger. - 1664-5464. ; 1:1, s. 103-112
- Related links:
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http://www.karger.co...
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https://www.karger.c...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- AIM: To study long-term effects of dietary patterns on dementia and Alzheimer's disease (AD). METHODS: Of 525 subjects randomly selected from population-based cohorts surveyed at midlife, a total of 385 (73%) subjects were re-examined 14 years later in the CAIDE study. A healthy-diet index (range 0-17) was constructed including both healthy and unhealthy dietary components. RESULTS: Persons with a healthy diet (healthy-diet index >8 points) had a decreased risk of dementia (OR 0.12, 95% CI 0.02-0.85) and AD (OR 0.08, 95% CI 0.01-0.89) compared with persons with an unhealthy diet (0-8 points), adjusting for several possible confounders. CONCLUSIONS: Healthy diet at midlife is associated with a decreased risk of dementia/AD in late life. These findings highlight the importance of dietary patterns and may make more effective measures for dementia/AD prevention or postponement possible.
Keyword
- Alzheimer’s disease
- cohort studies
- dementia
- diet
- population-based studies
- risk factors
Publication and Content Type
- ref (subject category)
- art (subject category)
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