Renal function is a determinant of subjective well-being in active seniors but not in patients with subjective memory complaints

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: onr:"swepub:oai:DiVA.org:umu-100435" > Renal function is a...

1 av 1
Föregående post
Nästa post
Till träfflistan

Olsson, Lovisa A.,1950-Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Department of Laboratory Medicine/Clinical Chemistry, Örebro University Hospital, Örebro, Sweden (författare)

Renal function is a determinant of subjective well-being in active seniors but not in patients with subjective memory complaints

Artikel/kapitelEngelska2014

Förlag, utgivningsår, omfång ...

2014-09-15
Springer Science and Business Media LLC,2014
electronicrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:umu-100435
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-100435URI
https://doi.org/10.1186/1756-0500-7-647DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-43262URI

Kompletterande språkuppgifter

Språk:engelska
Sammanfattning på:engelska

Ingår i deldatabas

SwePubSwePub

Klassifikation

Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

BACKGROUND: During our whole life span, factors influencing health and functioning are accumulated. In chronic kidney disease, quality of life is adversely affected. We hypothesized that biomarkers of renal function could also be determinants of subjective well-being (SWB) in Swedish elderly subjects. SWB was assessed by the Psychological General Well-Being index (PGWB index) in two study groups: Active seniors (AS) consisted of community-dwelling elderly Swedes leading an active life (n = 389), and the DGM cohort (n = 300) consisted of subjects referred to the Memory Unit at the Department of Geriatrics for memory problems, Serum creatinine, cystatin C, and eGFR (CKD-EPI) were used as biomarkers of renal function.RESULTS: There were no significant differences in cystatin C and eGFR values between the two cohorts: cystatin C medians 0.88 vs 0.86 mg/L and eGFR 73 vs 80 mL/min/1.73 m2 (AS vs DGM). In the AS cohort cystatin C was negatively related to PGWB index in women (P < 0.001, R2 ≈ 5%), and the covariates age and BMI did not improve the models. The renal biomarkers were unrelated to the PGWB index in the DGM cohort. Cystatin C in the AS cohort was adversely related to the PGWB subdimensions anxiety, depressed mood, positive well-being, and vitality in women, but in men only to depressed mood (P < 0.006; R2 ≈ 6%). In the DGM cohort, depressed mood in men was also significantly related to cystatin C (P = 0.050), but not in women.CONCLUSIONS: Renal function even within the normal range, measured by serum cystatin C concentration, has significant and sex specific associations with subjective well-being and its subdimensions in healthy elderly subjects. Maintenance of good renal function in aging may be of importance in maintaining a high subjective well-being.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Medicinsk bioteknologi Biomedicinsk laboratorievetenskap/teknologi hsv//swe
MEDICAL AND HEALTH SCIENCES Medical Biotechnology Biomedical Laboratory Science/Technology hsv//eng
Creatinine
Cystatin C
Subjective well-being
Biomarkers
Elderly
Renal function

Biuppslag (personer, institutioner, konferenser, titlar ...)

Hagnelius, Nils-Olof,1953-Region Örebro län,Department of Geriatrics, Örebro University Hospital, Örebro, Sweden(Swepub:oru)nhs (författare)
Nilsson, TorbjörnUmeå universitet,Institutionen för medicinsk biovetenskap,Department of Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden(Swepub:oru)tnnn (författare)
Örebro universitetInstitutionen för hälsovetenskap och medicin (creator_code:org_t)

Sammanhörande titlar

Ingår i:BMC Research Notes: Springer Science and Business Media LLC7, s. 647-1756-0500

Internetlänk

Hitta via bibliotek

BMC Research Notes (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

1 av 1
Föregående post
Nästa post
Till träfflistan

Hitta mer i SwePub

Av författaren/redakt...: Olsson, Lovisa A ...; Hagnelius, Nils- ...; Nilsson, Torbjör ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Medicinsk biotek ...; och Biomedicinsk lab ...

Artiklar i publikationen: BMC Research Not ...

Av lärosätet: Umeå universitet; Örebro universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se