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  • Beulens, J. W. J. (author)

Alcohol consumption and risk of type 2 diabetes in European men and women : influence of beverage type and body size The EPIC-InterAct study

  • Article/chapterEnglish2012

Publisher, publication year, extent ...

  • 2012-05-08
  • Wiley-Blackwell,2012
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-104250
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-104250URI
  • https://doi.org/10.1111/j.1365-2796.2012.02532.xDOI
  • https://lup.lub.lu.se/record/3132782URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Group Author: InterAct Consortium
  • Objective: To investigate the association between alcohol consumption and type 2 diabetes, and determine whether this is modified by sex, body mass index (BMI) and beverage type. Design: Multicentre prospective casecohort study. Setting: Eight countries from the European Prospective Investigation into Cancer and Nutrition cohort. Subjects: A representative baseline sample of 16 154 participants and 12 403 incident cases of type 2 diabetes. Interventions: Alcohol consumption assessed using validated dietary questionnaires. Main outcome measures: Occurrence of type 2 diabetes based on multiple sources (mainly self-reports), verified against medical information. Results: Amongst men, moderate alcohol consumption was nonsignificantly associated with a lower incidence of diabetes with a hazard ratio (HR) of 0.90 (95% CI: 0.781.05) for 6.112.0 versus 0.16.0 g day-1, adjusted for dietary and diabetes risk factors. However, the lowest risk was observed at higher intakes of 24.196.0 g day-1 with an HR of 0.86 (95% CI: 0.750.98). Amongst women, moderate alcohol consumption was associated with a lower incidence of diabetes with a hazard ratio of 0.82 (95% CI: 0.720.92) for 6.112.0 g day-1 (P interaction gender <0.01). The inverse association between alcohol consumption and diabetes was more pronounced amongst overweight (BMI = 25 kg m-2) than normal-weight men and women (P interaction < 0.05). Adjusting for waist and hip circumference did not alter the results for men, but attenuated the association for women (HR=0.90, 95% CI: 0.791.03 for 6.112.0 g day-1). Wine consumption for men and fortified wine  consumption for women were most strongly associated with a reduced risk of diabetes. Conclusions: The results of this study show that moderate alcohol consumption is associated with a lower risk of type 2 diabetes amongst women only. However, this risk reduction is in part explained by fat distribution. The relation between alcohol consumption and type 2 diabetes was stronger for overweight than normal-weight women and men.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • van der Schouw, Y. T. (author)
  • Bergmann, M. M. (author)
  • Rohrmann, S. (author)
  • Schulze, M. B. (author)
  • Buijsse, B. (author)
  • Grobbee, D. E. (author)
  • Arriola, L. (author)
  • Cauchi, S. (author)
  • Tormo, M-J (author)
  • Allen, N. E. (author)
  • van der A, D. L. (author)
  • Balkau, B. (author)
  • Boeing, H. (author)
  • Clavel-Chapelon, F. (author)
  • de Lauzon-Guillan, B. (author)
  • Franks, PaulLund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups(Swepub:lu)med-plf (author)
  • Froguel, P. (author)
  • Gonzales, C. (author)
  • Halkjaer, J. (author)
  • Huerta, J. M. (author)
  • Kaaks, R. (author)
  • Key, T. J. (author)
  • Khaw, K. T. (author)
  • Krogh, V. (author)
  • Molina-Montes, E. (author)
  • Nilsson, P. (author)
  • Overvad, K. (author)
  • Palli, D. (author)
  • Panico, S. (author)
  • Ramón Quirós, J. (author)
  • Rolandsson, OlovUmeå universitet,Allmänmedicin(Swepub:umu)olro0005 (author)
  • Romieu, I. (author)
  • Romaguera, D. (author)
  • Sacerdote, C. (author)
  • Sánchez, M-J (author)
  • Spijkerman, A. M. W. (author)
  • Teucher, B. (author)
  • Tjonneland, A. (author)
  • Tumino, R. (author)
  • Sharp, S. (author)
  • Forouhi, N. G. (author)
  • Langenberg, C. (author)
  • Feskens, E. J. M. (author)
  • Riboli, E. (author)
  • Wareham, N. J. (author)
  • Genomik, diabetes och endokrinologiForskargrupper vid Lunds universitet (creator_code:org_t)

Related titles

  • In:Journal of Internal Medicine: Wiley-Blackwell272:4, s. 358-3700954-68201365-2796

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