Chemosensory perception, symptoms and autonomic responses during chemical exposure in multiple chemical sensitivity

Andersson, Linus (author): Högskolan i Gävle,Arbetshälsovetenskap,Centrum för belastningsskadeforskning

Claeson, Anna-Sara, 1974- (author): Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden

Dantoft, Thomas Meinertz (author): Danish Research Centre for Chemical Sensitivities, Copenhagen University Hospital Gentofte, Gentofte, Denmark; Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark

Skovbjerg, Sine (author): Danish Research Centre for Chemical Sensitivities, Copenhagen University Hospital Gentofte, Gentofte, Denmark

Lind, Nina, 1989- (author): Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden

Nordin, Steven, 1960- (author): Umeå universitet,Institutionen för psykologi,Department of Psychology, Umeå University, Umeå, Sweden

(creator_code:org_t)

2015-04-28
2016
English.
In: International Archives of Occupational and Environmental Health. - : Springer. - 0340-0131 .- 1432-1246. ; 89:1, s. 79-88

Related links:: https://urn.kb.se/re...; show more...; https://doi.org/10.1...; https://urn.kb.se/re...; show less...

Abstract Subject headings

Purpose: Multiple chemical sensitivity (MCS) is a prevalent medically unexplained symptom characterized by symptom reactions to everyday chemical exposure below hygienic thresholds. The aim of this study was to investigate the expressions of hyper-reactivity in MCS during whole-body exposure to low concentrations of the odorant n-butanol.Methods: We exposed 18 participants with MCS and 18 non-ill controls to a low concentration of the odorantn-butanol using an exposure chamber. The first 10 min constituted blank exposure, after which then-butanol concentration increased and reached a plateau at 11.5 mg/m3.Results: MCS participants, compared with controls, reported greater perceived odor intensities, more unpleasantness to the exposure and increasing symptoms over time. MCS participants also expressed higher pulse rate and lower pulse rate variability than controls did. No group differences were found for breathing rate or tonic electrodermal activity responses.Conclusions: We conclude that MCS sufferers differ from healthy controls in terms of autonomic responses, symptoms and chemosensory perception during chemical exposure.

MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Annan hälsovetenskap (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Other Health Sciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)

By the author/editor: Andersson, Linus; Claeson, Anna-Sa ...; Dantoft, Thomas ...; Skovbjerg, Sine; Lind, Nina, 1989 ...; Nordin, Steven, ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Other Health Sci ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Occupational Hea ...

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