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Phrenic nerve trans...
Phrenic nerve transfer in the treatment of brachial plexus avulsion : an experimental study of nerve regeneration and muscle morphology in rats.
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- Zhang, Cheng-Gang (author)
- Umeå universitet,Anatomi
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Ma, Jian-Jun (author)
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Terenghi, Giorgio (author)
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Mantovani, Cristina (author)
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- Wiberg, Mikael (author)
- Umeå universitet,Anatomi,Handkirurgi
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(creator_code:org_t)
- Wiley, 2004
- 2004
- English.
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In: Microsurgery. - : Wiley. - 0738-1085 .- 1098-2752. ; 24:3, s. 232-240
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- The regeneration of motor and sensory neurons and the morphological changes of the target muscle after phrenic nerve transfer were investigated in adult rats. Six months following nerve transfer, 326.0 +/- 16.31 phrenic motoneurons regenerated into musculocutaneous nerve, which is not different from the normal number of phrenic motoneurons. The regenerated motoneurons exhibited a 14% nonsignificant hypertrophy. Of the dorsal root ganglia (DRG) neurons, 255.8 +/- 45.26 regenerated, which was significantly lower than the number of normal phrenic DRG neurons. The regenerated phrenic DRG neurons showed a 24% close-to-significant atrophy. The target muscle fiber morphology changed considerably after reinnervation. The present results suggest that the phrenic nerve has very good regenerative ability in terms of its motoneurons and a relatively insufficient sensory neuronal regeneration.
Keyword
- Animals
- Brachial Plexus Neuropathies/*surgery
- Disease Models; Animal
- Female
- Motor Neurons/ultrastructure
- Muscle Fibers/*ultrastructure
- Muscle; Skeletal/physiology/ultrastructure
- Musculocutaneous Nerve/ultrastructure
- Nerve Regeneration/*physiology
- Nerve Transfer/*methods
- Phrenic Nerve/*transplantation
- Rats
- Rats; Sprague-Dawley
- Reference Values
Publication and Content Type
- ref (subject category)
- art (subject category)
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