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Increased plasma le...
Increased plasma levels of soluble CD23 in haemorrhagic fever with renal syndrome; relation to virus-specific IgE.
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Alexeyev, O A (author)
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Linderholm, M (author)
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- Elgh, Fredrik, 1957- (author)
- Umeå universitet,Virologi,Fredrik Elgh
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Wadell, G (author)
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Juto, P (author)
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Tärnvik, A (author)
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(creator_code:org_t)
- 1997
- 1997
- English.
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In: Clinical and Experimental Immunology. - 0009-9104 .- 1365-2249. ; 109:2, s. 351-5
- Related links:
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https://urn.kb.se/re...
Abstract
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- In 15 consecutive patients hospitalized with nephropathia epidemica, a European form of haemorrhagic fever with renal syndrome (HFRS) caused by Puumala virus, plasma concentrations of soluble CD23 (sCD23) and Puumala virus-specific IgE were determined. In the acute phase of illness, 11/15 patients had increased sCD23 levels (> 91 U/ml), whereas in convalescence, values of 8/10 patients were normalized. Maximal sCD23 values were correlated to maximal concentrations of Puumala virus-specific serum IgE (r = 0.597; P = 0.025). The results are compatible with a known ability of sCD23 to augment IgE production.
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- ref (subject category)
- art (subject category)
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