Search: onr:"swepub:oai:DiVA.org:umu-144812" > Indoor bacteria and...
Fältnamn | Indikatorer | Metadata |
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000 | 05651naa a2200541 4500 | |
001 | oai:DiVA.org:umu-144812 | |
003 | SwePub | |
008 | 180215s2018 | |||||||||||000 ||eng| | |
009 | oai:DiVA.org:uu-346883 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1448122 URI |
024 | 7 | a https://doi.org/10.1183/13993003.01241-20172 DOI |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3468832 URI |
040 | a (SwePub)umud (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Pekkanen, Juhau Univ Helsinki, Dept Publ Hlth, Helsinki, Finland.;Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.4 aut |
245 | 1 0 | a Indoor bacteria and asthma in adults :b a multicentre case-control study within ECRHS II |
264 | c 2018-02-07 | |
264 | 1 | b European Respiratory Society (ERS),c 2018 |
338 | a print2 rdacarrier | |
520 | a Both protective and adverse effects of indoor microbial exposure on asthma have been reported, but mostly in children. To date, no study in adults has used non-targeted methods for detection of indoor bacteria followed by quantitative confirmation. A cross-sectional study of 198 asthmatic and 199 controls was conducted within the European Community Respiratory Health Survey (ECRHS) II. DNA was extracted from mattress dust for bacterial analysis using denaturing gradient gel electrophoresis (DGGE). Selected bands were sequenced and associations with asthma confirmed with four quantitative PCR (qPCR) assays. 15 out of 37 bands detected with DGGE, which had at least a suggestive association (p<0.25) with asthma, were sequenced. Of the four targeted qPCRs, Clostridium cluster XI confirmed the protective association with asthma. The association was dose dependent (aOR 0.43 (95% CI 0.22-0.84) for the fourth versus first quartile, p for trend 0.009) and independent of other microbial markers. Few significant associations were observed for the three other qPCRs used. In this large international study, the level of Clostridium cluster XI was independently associated with a lower risk of prevalent asthma. Results suggest the importance of environmental bacteria also in adult asthma, but need to be confirmed in future studies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng |
700 | 1 | a Valkonen, Mariau Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.;Univ Eastern Finland, Dept Environm & Biol Sci, Kuopio, Finland.4 aut |
700 | 1 | a Täubel, Martinu Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.4 aut |
700 | 1 | a Tischer, Christinau ISGlobal, Barcelona Inst Global Hlth, Barcelona, Spain.;Univ Pompeu Fabra, Barcelona, Spain.;CIBER Epidemiol Salud Publ, CIBERESP, Madrid, Spain.4 aut |
700 | 1 | a Leppänen, Hannau Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.4 aut |
700 | 1 | a Kärkkäinen, Päivi Mu Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.4 aut |
700 | 1 | a Rintala, Helenau Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.4 aut |
700 | 1 | a Zock, Jan-Paulu ISGlobal, Barcelona Inst Global Hlth, Barcelona, Spain.;Univ Pompeu Fabra, Barcelona, Spain.;CIBER Epidemiol Salud Publ, CIBERESP, Madrid, Spain.4 aut |
700 | 1 | a Casas, Lidiau Katholieke Univ Leuven, Ctr Environm & Hlth, Dept Publ Hlth & Primary Care, Leuven, Belgium.4 aut |
700 | 1 | a Probst-Hensch, Nicoleu Swiss Trop & Publ Hlth Inst, Dept Epidemiol & Publ Hlth, Basel, Switzerland.;Univ Basel, Dept Publ Hlth, Basel, Switzerland.4 aut |
700 | 1 | a Forsberg, Bertilu Umeå universitet,Yrkes- och miljömedicin,Umea Univ, Dept Publ Hlth & Clin Med Occupat & Environm Me, Umea, Sweden.4 aut0 (Swepub:umu)befo0001 |
700 | 1 | a Holm, Mathiasu Sahlgrens Univ Hosp, Dept Occupat & Environm Med, Gothenburg, Sweden.4 aut |
700 | 1 | a Janson, Christeru Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)chrisjn |
700 | 1 | a Pin, Isabelleu Univ Grenoble Alpes, CHU Grenoble Alpes, Grenoble, France.4 aut |
700 | 1 | a Gislason, Thorarinnu Landspitali Univ Hosp, Dept Resp Med & Sleep, E7, Reykjavik, Iceland.;Univ Iceland, Fac Med, Reykjavik, Iceland.4 aut |
700 | 1 | a Jarvis, Debbieu Natl Heart & Lung Inst, Imperial Coll, Populat Hlth & Occupat Dis, London, England.;Imperial Coll, MRC PHE Ctr Environm & Hlth, London, England.4 aut |
700 | 1 | a Heinrich, Joachimu Ludwig Maximillians Univ Munich, Univ Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany.;German Res Ctr Environm Hlth, Inst Epidemiol 1, Helmholtz Zentrum Munchen, Neuherberg, Germany.4 aut |
700 | 1 | a Hyvärinen, Anneu Univ Helsinki, Dept Publ Hlth, Helsinki, Finland.4 aut |
710 | 2 | a Univ Helsinki, Dept Publ Hlth, Helsinki, Finland.;Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.b Natl Inst Hlth & Welf, Living Environm & Hlth Unit, Kuopio, Finland.;Univ Eastern Finland, Dept Environm & Biol Sci, Kuopio, Finland.4 org |
773 | 0 | t European Respiratory Journald : European Respiratory Society (ERS)g 51:2q 51:2x 0903-1936x 1399-3003 |
856 | 4 | u https://erj.ersjournals.com/content/erj/51/2/1701241.full.pdf |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-144812 |
856 | 4 8 | u https://doi.org/10.1183/13993003.01241-2017 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-346883 |
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