SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:umu-149920"
 

Sökning: onr:"swepub:oai:DiVA.org:umu-149920" > Conservative manage...

  • La Russa, M (författare)

Conservative management of endometrial cancer : a survey amongst European clinicians

  • Artikel/kapitelEngelska2018

Förlag, utgivningsår, omfång ...

  • 2018-06-26
  • Springer Science and Business Media LLC,2018
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-149920
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-149920URI
  • https://doi.org/10.1007/s00404-018-4820-7DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • OBJECTIVE: To investigate differences and similarities in the clinical approach of young clinicians managing women with endometrial cancer (EC) conservatively.METHODS: A web-based survey was carried out. A platform of the European Network of Young Gynaecological Oncologists (ENYGO) database was used. A 38-item multiple-choice questionnaire was used to evaluate current practice in fertility-sparing management of EC. The survey covered investigations, treatment options, follow-up and management of recurrence and future family planning. Descriptive statistics were used.RESULTS: Overall, 116 out of 650 (17.84%) ENYGO members responded to the survey. In 92 (79.3%) centres, the caseload of early stage EC treated conservatively was less than 10 per year. One hundred and seven responders (93.8%) believe that treatment with progestins could be offered in grade 1 EC without myometrial invasion, but a minority would recommend it even for grade 2 tumours with no myometrial invasion or grade 1 with superficial invasion. The diagnostic tool for establishing grade of tumour was hysteroscopy with dilatation and curettage in 64 (55%) centres. Medroxyprogesterone acetate represents the most commonly prescribed progestogen (55, 47.4%). In 78 (67.2%) centres, a repeat endometrial biopsy was offered after 3 months of treatment commencement. Recurrences are treated mostly with hysterectomy (81, 69.9%) with only a small number of responders recommending to repeat progestin treatment. Lynch syndrome is a contraindication for conservative management in half of the responders (57, 49.1%). Most clinicians agree that patients should be referred promptly for assisted reproductive techniques once complete response has been achieved (68, 58.6%).CONCLUSIONS: Our study shows that conservative management is increasingly offered to women affected by early stage EC wishing to preserve their fertility. Further studies and joint registries are required to evaluate safety and effectiveness of this approach in this probably growing number of patients.

Ämnesord och genrebeteckningar

  • Assisted reproduction
  • Conservative management
  • Endometrial cancer
  • Pregnancies
  • Progestins
  • Obstetrics and Gynaecology
  • obstetrik och gynekologi
  • onkologi
  • Oncology

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Zapardiel, I (författare)
  • Halaska, M J (författare)
  • Zalewski, K (författare)
  • Laky, R (författare)
  • Dursun, P (författare)
  • Lindquist, DavidUmeå universitet,Onkologi(Swepub:umu)dali0066 (författare)
  • Sukhin, V (författare)
  • Polterauer, S (författare)
  • Biliatis, I (författare)
  • Umeå universitetOnkologi (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Archives of Gynecology and Obstetrics: Springer Science and Business Media LLC298, s. 373-3800932-00671432-0711

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy