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Role of BASIC PENTA...
Role of BASIC PENTACYSTEINE transcription factors in a subset of cytokinin signaling responses
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Shanks, Carly M. (author)
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Hecker, Andreas (author)
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Cheng, Chia-Yi (author)
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Brand, Luise (author)
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- Collani, Silvio (author)
- Umeå universitet,Umeå Plant Science Centre (UPSC),Institutionen för fysiologisk botanik,Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany
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- Schmid, Markus (author)
- Umeå universitet,Umeå Plant Science Centre (UPSC),Institutionen för fysiologisk botanik
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Schaller, G. Eric (author)
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Wanke, Dierk (author)
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Harter, Klaus (author)
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Kieber, Joseph J. (author)
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(creator_code:org_t)
- 2018-06-17
- 2018
- English.
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In: The Plant Journal. - : John Wiley & Sons. - 0960-7412 .- 1365-313X. ; 95:3, s. 458-473
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Cytokinin plays diverse roles in plant growth and development, generally acting by modulating gene transcription in target tissues. The type-B Arabidopsis response regulators (ARR) transcription factors have emerged as primary targets of cytokinin signaling and are required for essentially all cytokinin-mediated changes in gene expression. The diversity of cytokinin function is likely imparted by the activity of various transcription factors working with the type-B ARRs to alter specific sets of target genes. One potential set of co-regulators modulating the cytokinin response are the BARLEY B-RECOMBINANT/BASIC PENTACYSTEINE (BBR/BPC) family of plant-specific transcription factors. Here, we show that disruption of multiple BPCs results in reduced sensitivity to cytokinin. Further, the BPCs are necessary for the induction of a subset of genes in response to cytokinin. We identified direct invivo targets of BPC6 using ChIP-Seq and found an enrichment of promoters of genes differentially expressed in response to cytokinin. Further, a significant number of BPC6 regulated genes are also direct targets of the type-B ARRs. Potential cis-binding elements for a number of other transcription factors linked to cytokinin action are enriched in the BPC binding fragments, including those for the cytokinin response factors (CRFs). In addition, several BPCs interact with a subset of type-A ARRs. Consistent with these results, a significant number of genes whose expression is altered in bpc mutant roots are also mis-expressed in crf1,3,5,6 and type-A arr3,4,5,6,7,8,9,15 mutant roots. These results suggest that the BPCs are part of a complex network of transcription factors that are involved in the response to cytokinin.
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Keyword
- Arabidopsis thaliana
- ChIP-Seq
- cytokinin
- phytohormones
- transcription factor
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Shanks, Carly M.
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Hecker, Andreas
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Cheng, Chia-Yi
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Brand, Luise
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Collani, Silvio
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Schmid, Markus
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show more...
-
Schaller, G. Eri ...
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Wanke, Dierk
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Harter, Klaus
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Kieber, Joseph J ...
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show less...
- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Biochemistry and ...
- Articles in the publication
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The Plant Journa ...
- By the university
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Umeå University