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Physical activity a...
Physical activity and incidence of restrictive spirometry pattern in adults
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- Carsin, Anne-Elie (author)
- Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
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- Keidel, Dirk (author)
- Swiss Trop & Publ Hlth Inst, Basel, Switzerland
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- Fuertes, Elaine (author)
- Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
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- Imboden, Medea (author)
- Swiss Trop & Publ Hlth Inst, Basel, Switzerland
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- Weyler, Joost (author)
- Dept Epidemiol & Social Med, Antwerp, Belgium
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- Nowak, Dennis (author)
- Univ Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany
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- Heinrich, Joachim (author)
- Univ Hosp Munich, Inst & Outpatient Clin Occupat Social & Environm, Munich, Germany
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- Urrutia, Isabel (author)
- Galdakao Hosp, Galdakao, Spain
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- Martinez-Moratalla, Jose (author)
- Complejo Hosp Univ, Albacete, Spain
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- Caviezel, S. (author)
- Swiss Trop & Publ Hlth Inst, Basel, Switzerland
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- Beckmeyer-Borowko, A. (author)
- Swiss Trop & Publ Hlth Inst, Basel, Switzerland,Imperial Coll London, London, England
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- Raherison, Chantal (author)
- Bordeaux Univ, U1219, Bordeaux, France
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- Pin, Isabelle (author)
- CHU Grenoble Alpes, Grenoble, France
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- Demoly, Pascal (author)
- Univ Hosp Montpellier, Hop Arnaud Villeneuve, Dept Pneumol & Addictol, Montpellier, France
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- Leynaert, Benedicte (author)
- Univ Paris Diderot, INSERM, Equipe Epidemiol, UMR 1152, Paris, France
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- Cerveri, I. (author)
- Univ Pavia, Pavia, Italy
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- Bono, Roberto (author)
- Univ Turin, Dept Publ Hlth & Pediat, Turin, Italy
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- Accordini, Simone (author)
- Univ Verona, Dipartimento Diagnost & Sanita Pubbl, Verona, Italy
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Amaral, A. (author)
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- Gislason, Thorarig (author)
- Univ Iceland, Reykjavik, Iceland
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- Svanes, Cecilie (author)
- Univ Bergen, Dept Clin Sci, Bergen, Norway
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- Toren, K. (author)
- Univ Gothenburg, Gothenburg, Sweden
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- Forsberg, Bertil (author)
- Umeå universitet,Yrkes- och miljömedicin,Umea Univ, Div Occupat & Environm Med, Umea, Sweden
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- Janson, Christer (author)
- Uppsala universitet,Lung- allergi- och sömnforskning
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- Dharmage, S. (author)
- Univ Melbourne, Melbourne Sch Populat & Global Hlth, Melbourne, Vic, Australia
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- Jogi, Rain (author)
- Tartu Univ Hosp, Lung Clin, Tartu, Estonia
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- Anto, Jm (author)
- Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
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- Probst-Hensch, Nicole (author)
- Swiss Trop & Publ Hlth Inst, Basel, Switzerland
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- Garcia-Aymerich, Judith (author)
- Ctr Res Environm Epidemiol CREAL, ISGlobal, Barcelona, Spain
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(creator_code:org_t)
- European Respiratory Society, 2018
- 2018
- English.
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In: European Respiratory Journal. - : European Respiratory Society. - 0903-1936 .- 1399-3003. ; 52
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
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- Introduction: A restrictive spirometry pattern is associated with high morbidity and mortality. Whether regular physical activity (PA) protects against this pattern has never been studied.Objective: To assess if PA is associated with the development of restrictive pattern.Methods: Lung function and PA were assessed in the second and third follow-up of the ECRHS (n=2757, 39-67 years) and SAPALDIA (n=2610, 36-82 y) cohorts. Subjects with restrictive or obstructive pattern at baseline were excluded. We assessed the association of being active at baseline (defined as exercising vigorously >2-3 times/wk for >1 h) and restrictive pattern at follow-up (defined as a post-bronchodilator FEV1/FVC≥LLN and FVC<80% pred.) using modified Poisson regression, adjusting for age, sex, smoking and asthma. We explored the impact of adjusting for baseline FVC. Additionally, models were repeated stratified by BMI.Results: After 10 years follow-up, 3.7% and 2.8% of participants developed a restrictive pattern, in ECRHS and SAPALDIA respectively. In both cohorts, being physically active was associated with lower risk of a restrictive pattern (meta-analysed RR 0.65, 95% CI 0.47-0.89). This association was stronger in overweight (0.41, 0.23-0.75) and obese (0.42, 0.17-1.05) than in normal weight subjects, but was attenuated when adjusting for baseline FVC (0.77, 0.58-1.04).Conclusion: In two large European studies, adults who reported more PA were at lower risk of developing a restrictive spirometry pattern. Lung function at baseline seemed to explain part of the observed association, stressing the need of adequate method to take into account both horse-racing and regression-to-the-means effects.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Publication and Content Type
- vet (subject category)
- art (subject category)
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- By the author/editor
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Carsin, Anne-Eli ...
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Keidel, Dirk
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Fuertes, Elaine
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Imboden, Medea
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Weyler, Joost
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Nowak, Dennis
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show more...
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Heinrich, Joachi ...
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Urrutia, Isabel
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Martinez-Moratal ...
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Caviezel, S.
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Beckmeyer-Borowk ...
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Raherison, Chant ...
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Pin, Isabelle
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Demoly, Pascal
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Leynaert, Benedi ...
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Cerveri, I.
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Bono, Roberto
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Accordini, Simon ...
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Amaral, A.
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Gislason, Thorar ...
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Svanes, Cecilie
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Toren, K.
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Forsberg, Bertil
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Janson, Christer
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Dharmage, S.
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Jogi, Rain
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Anto, Jm
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Probst-Hensch, N ...
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Garcia-Aymerich, ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Respiratory Medi ...
- Articles in the publication
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European Respira ...
- By the university
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Umeå University
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Uppsala University