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One hundred eleven ...
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Asplund, PärUmeå universitet,Klinisk neurovetenskap
(author)
One hundred eleven Percutaneous Balloon Compressions for Trigeminal Neuralgia in a Cohort of 66 Patients with Multiple Sclerosis
- Article/chapterEnglish2019
Publisher, publication year, extent ...
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2019-11
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Oxford University Press,2019
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LIBRIS-ID:oai:DiVA.org:umu-158351
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-158351URI
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https://doi.org/10.1093/ons/opy402DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:142478268URI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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BACKGROUND: Trigeminal neuralgia associated with multiple sclerosis (MS-TN) is comparatively rare and larger series of percutaneous balloon compression (PBC) in such cases are few in the literature.OBJECTIVE: To evaluate the results after PBC for MS-TN with regards to therapeutic effect, side effects, and complications.METHODS: One hundred eleven procedures with PBC performed in 66 cases of MS-TN were analyzed. Therapeutic effect was measured as postoperative time to pain recurrence without medication. All complications were compiled and the sensory function was evaluated in a subgroup of cases.RESULTS: The initial pain free rate was 67% and the median time to pain recurrence was 8 mo. Thirty-six patients were treated with PBC only, and among them, the results were worse if treated 3 to 4 times before, compared to first treatment (P = .009-.034). Patients who had several PBCs had worse results already after the first surgery (P < .001). A significant number of patients had impaired sensation to light touch directly after surgery, which was normalized at the late follow-up. Sensimetric testing showed raised thresholds for perception and pain directly after surgery (P = .004-.03), but these were also normalized at the late follow-up.CONCLUSION: PBC is a treatment that can be effective for many patients with MS-TN. Repeated previous surgeries is a risk factor for an unsatisfactory outcome. However, the patients with multiple surgeries had less satisfactory results already at the first procedure, indicating that a therapy resistant disease can be predicted after the first two PBCs. Postoperative sensory deficits were common but not lasting.
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Linderoth, BengtKarolinska Institutet
(author)
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Lind, GöranKarolinska Institutet
(author)
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Winter, Jaleh
(author)
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Bergenheim, A. TommyUmeå universitet,Klinisk neurovetenskap(Swepub:umu)tobe0004
(author)
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Umeå universitetKlinisk neurovetenskap
(creator_code:org_t)
Related titles
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In:Operative Neurosurgery: Oxford University Press17:5, s. 452-4592332-42522332-4260
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