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Enzymes for pharmac...
Enzymes for pharmaceutical and therapeutic applications
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Meghwanshi, Gautam Kumar (author)
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Kaur, Navpreet (author)
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Verma, Swati (author)
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Dabi, Narendra Kumar (author)
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Vashishtha, Abhishek (author)
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Charan, P. D. (author)
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Purohit, Praveen (author)
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Bhandari, H. S. (author)
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Bhojak, N. (author)
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- Kumar, Rajender (author)
- Umeå universitet,Institutionen för klinisk mikrobiologi
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(creator_code:org_t)
- 2020-05-08
- 2020
- English.
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In: Biotechnology and applied biochemistry. - : John Wiley & Sons. - 0885-4513 .- 1470-8744. ; 67:4, s. 586-601
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Abstract
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- Enzymes are highly efficient and selective biocatalysts, present in the living beings. They exist in enormous varieties in terms of the types of reactions catalyzed by them for instance oxidation-reduction, group transfers within the molecules or between the molecules, hydrolysis, isomerization, ligation, bond cleavage, and bond formation. Besides, enzyme based catalyses are performed with much higher fidelity, under mild reaction conditions and are highly efficient in terms of number of steps, giving them an edge over their chemical counter parts. The unique characteristics of enzymes makes them highly applicable fora number of chemical transformation reactions in pharmaceutical industries, such as group protection and deprotection, selective acylation and deacylation, selective hydrolysis, deracemization, kinetic resolution of racemic mixtures, esterification, transesterification, and many others. In this review, an overview of the enzymes, their production and their applications in pharmaceutical syntheses and enzyme therapies are presented with diagrams, reaction schemes and table for easy understanding of the readers.
Subject headings
- TEKNIK OCH TEKNOLOGIER -- Industriell bioteknik -- Biokatalys och enzymteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Industrial Biotechnology -- Biocatalysis and Enzyme Technology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
Keyword
- enzyme
- fermentation
- antimicrobials
- enzyme therapy
- infectious diseases
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- By the author/editor
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Meghwanshi, Gaut ...
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Kaur, Navpreet
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Verma, Swati
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Dabi, Narendra K ...
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Vashishtha, Abhi ...
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Charan, P. D.
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show more...
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Purohit, Praveen
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Bhandari, H. S.
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Bhojak, N.
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Kumar, Rajender
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show less...
- About the subject
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Industrial Biote ...
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and Biocatalysis and ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Biochemistry and ...
- Articles in the publication
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Biotechnology an ...
- By the university
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Umeå University