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Development and use of health outcome descriptors : a guideline development case study

Baldeh, Tejan (author)
Saz-Parkinson, Zuleika (author)
Muti, Paola (author)
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Santesso, Nancy (author)
Morgano, Gian Paolo (author)
Wiercioch, Wojtek (author)
Nieuwlaat, Robby (author)
Gräwingholt, Axel (author)
Broeders, Mireille (author)
Duffy, Stephen (author)
Hofvind, Solveig (author)
Nyström, Lennarth, 1944- (author)
Umeå universitet,Institutionen för epidemiologi och global hälsa,European Commission Initiative on Breast Cancer Guidelines Development Group, European Commission, JRC, Ispra, Italy
Ioannidou-Mouzaka, Lydia (author)
Warman, Sue (author)
McGarrigle, Helen (author)
Knox, Susan (author)
Fitzpatrick, Patricia (author)
Rossi, Paolo Giorgi (author)
Quinn, Cecily (author)
Borisch, Bettina (author)
Lebeau, Annette (author)
de Wolf, Chris (author)
Langendam, Miranda (author)
Piggott, Thomas (author)
Giordano, Livia (author)
Van Landsveld-Verhoeven, Cary (author)
Bernier, Jacques (author)
Rabe, Peter (author)
Schunemann, Holger J. (author)
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 (creator_code:org_t)
2020-06-05
2020
English.
In: Health and Quality of Life Outcomes. - : BioMed Central. - 1477-7525. ; 18:1
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https://umu.diva-por... (primary) (Raw object)
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Background: During healthcare guideline development, panel members often have implicit, different definitions of health outcomes that can lead to misunderstandings about how important these outcomes are and how to balance benefits and harms. McMaster GRADE Centre researchers developed ‘health outcome descriptors’ for standardizing descriptions of health outcomes and overcoming these problems to support the European Commission Initiative on Breast Cancer (ECIBC) Guideline Development Group (GDG). We aimed to determine which aspects of the development, content, and use of health outcome descriptors were valuable to guideline developers.Methods: We developed 24 health outcome descriptors related to breast cancer screening and diagnosis for the European Commission Breast Guideline Development Group (GDG). Eighteen GDG members provided feedback in written format or in interviews. We then evaluated the process and conducted two health utility rating surveys.Results: Feedback from GDG members revealed that health outcome descriptors are probably useful for developing recommendations and improving transparency of guideline methods. Time commitment, methodology training, and need for multidisciplinary expertise throughout development were considered important determinants of the process. Comparison of the two health utility surveys showed a decrease in standard deviation in the second survey across 21 (88%) of the outcomes.Conclusions: Health outcome descriptors are feasible and should be developed prior to the outcome prioritization step in the guideline development process. Guideline developers should involve a subgroup of multidisciplinary experts in all stages of development and ensure all guideline panel members are trained in guideline methodology that includes understanding the importance of defining and understanding the outcomes of interest.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Health Care Service and Management, Health Policy and Services and Health Economy (hsv//eng)

Keyword

Health outcomes
Health states
Health utility
Guideline methodology

Publication and Content Type

ref (subject category)
art (subject category)

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