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A systematic approa...
A systematic approach for introduction of novel treatments to a chronic patient group : sacubitril-valsartan as a case study
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- Norberg, Helena (author)
- Umeå universitet,Institutionen för integrativ medicinsk biologi (IMB),Avdelningen för medicin
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- Bergdahl, Ellinor (author)
- Umeå universitet,Avdelningen för medicin
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- Hellström Ängerud, Karin (author)
- Umeå universitet,Institutionen för omvårdnad
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- Lindmark, Krister (author)
- Umeå universitet,Avdelningen för medicin
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(creator_code:org_t)
- 2020-08-21
- 2021
- English.
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In: European Journal of Clinical Pharmacology. - : Springer. - 0031-6970 .- 1432-1041. ; 77, s. 125-131
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Abstract
Subject headings
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- Purpose: To develop a model for systematic introduction and to test the feasibility in a chronic disease population. We also investigated how the approach was received by the patients.Methods and results: The systematic introduction approach is a seven-step procedure: step 1, define a few main criteria; step 2, primary scan patients with the one or two main criteria using computerized medical records/databases/clinical registries; step 3, identify patients applying the other predefined criteria; step 4, evaluate if any examinations/laboratory test updates are required; step 5, summon identified patients to the clinic with an information letter; step 6, discuss treatment with the patient and prescribe if appropriate; and step 7, follow up on initiated therapy and evaluate the applied process. The model was tested in a case study during introduction of the new drug sacubitril-valsartan in a heart failure population. In total, 76 out of 1924 patients were identified to be eligible for sacubitril-valsartan and summoned to the clinic to discuss treatment. Patient experiences with the approach were investigated in an interview study with general inductive approach using qualitative content analysis. This resulted in three final categories: a good approach, role of the information letter, and trust in care.Conclusions: The systematic introduction approach ensures that strict criteria are used in the selection process and that a treatment can be implemented in eligible patients within a specified population with limited resources and time. The model was effective in our case study and maintained the patient's confidence in healthcare.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Systematic implementation
- Healthcare quality improvement
- Chronic disease management
- Sacubitril-valsartan
Publication and Content Type
- ref (subject category)
- art (subject category)
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