Search: onr:"swepub:oai:DiVA.org:umu-178114" > Genome-wide associa...
Fältnamn | Indikatorer | Metadata |
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000 | 06236naa a2200757 4500 | |
001 | oai:DiVA.org:umu-178114 | |
003 | SwePub | |
008 | 210105s2020 | |||||||||||000 ||eng| | |
009 | oai:lup.lub.lu.se:fef5ff0c-bfc5-43f0-974f-6ec15c6340f2 | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1781142 URI |
024 | 7 | a https://doi.org/10.1038/s41597-020-00716-72 DOI |
024 | 7 | a https://lup.lub.lu.se/record/fef5ff0c-bfc5-43f0-974f-6ec15c6340f22 URI |
040 | a (SwePub)umud (SwePub)lu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Cai, Linau University of Cambridge4 aut |
245 | 1 0 | a Genome-wide association analysis of type 2 diabetes in the EPIC-InterAct study |
264 | c 2020-11-13 | |
264 | 1 | b Nature Publishing Group,c 2020 |
338 | a electronic2 rdacarrier | |
520 | a Type 2 diabetes (T2D) is a global public health challenge. Whilst the advent of genome-wide association studies has identified >400 genetic variants associated with T2D, our understanding of its biological mechanisms and translational insights is still limited. The EPIC-InterAct project, centred in 8 countries in the European Prospective Investigations into Cancer and Nutrition study, is one of the largest prospective studies of T2D. Established as a nested case-cohort study to investigate the interplay between genetic and lifestyle behavioural factors on the risk of T2D, a total of 12,403 individuals were identified as incident T2D cases, and a representative sub-cohort of 16,154 individuals was selected from a larger cohort of 340,234 participants with a follow-up time of 3.99 million person-years. We describe the results from a genome-wide association analysis between more than 8.9 million SNPs and T2D risk among 22,326 individuals (9,978 cases and 12,348 non-cases) from the EPIC-InterAct study. The summary statistics to be shared provide a valuable resource to facilitate further investigations into the genetics of T2D. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Endokrinologi och diabetes0 (SwePub)302052 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Endocrinology and Diabetes0 (SwePub)302052 hsv//eng |
700 | 1 | a Wheeler, Eleanoru University of Cambridge4 aut |
700 | 1 | a Kerrison, Nicola D.u University of Cambridge4 aut |
700 | 1 | a Luan, Jian'anu University of Cambridge4 aut |
700 | 1 | a Deloukas, Panosu Queen Mary University4 aut |
700 | 1 | a Franks, Paul W.u Umeå University,Lund University,Lunds universitet,Umeå universitet,Näringsforskning,Department of Clinical Sciences, Clinical Research Center, Skåne University Hospital, Lund University, 20502, Malmö, Sweden,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups4 aut0 (Swepub:lu)med-plf |
700 | 1 | a Amiano, Pilaru Biodonostia Health Research Institute4 aut |
700 | 1 | a Ardanaz, Evau Health Research Institute of Navarra (IDISNA)4 aut0 (Swepub:lu)extLU-05 |
700 | 1 | a Bonet, Catalinau Bellvitge Biomedical Research Institute4 aut |
700 | 1 | a Fagherazzi, Guyu Institut Gustave Roussy,Luxembourg Institute of Health4 aut |
700 | 1 | a Groop, Leif C.u Lund University,Lunds universitet,Translationell muskelforskning,Forskargrupper vid Lunds universitet,Translational Muscle Research,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)endo-lgr |
700 | 1 | a Kaaks, Rudolfu German Cancer Research Centre4 aut |
700 | 1 | a Huerta, Jose Mariau CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council4 aut |
700 | 1 | a Masala, Giovannau Institute for Cancer Research, Prevention and Clinical Network (ISPRO)4 aut |
700 | 1 | a Nilsson, Peter M.u Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups,Skåne University Hospital4 aut0 (Swepub:lu)medf-pni |
700 | 1 | a Overvad, Kimu Aarhus University,Aalborg University Hospital4 aut |
700 | 1 | a Pala, Valeriau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Panico, Salvatoreu University of Naples Federico II4 aut |
700 | 1 | a Rodriguez-Barranco, Miguelu Andalusian School Of Public Health (EASP),CIBER Epidemiology and Public Health (CIBERESP)4 aut |
700 | 1 | a Rolandsson, Olovu Umeå University,Umeå universitet,Allmänmedicin4 aut0 (Swepub:umu)olro0005 |
700 | 1 | a Sacerdote, Carlottau Citta' della Salute e della Scienza Hospital-University of Turin4 aut |
700 | 1 | a Schulze, Matthias B.u University of Potsdam,German Center for Diabetes Research4 aut |
700 | 1 | a Spijkerman, Annemieke M. W.u National Institute for Public Health and the Environment (RIVM)4 aut |
700 | 1 | a Tjonneland, Anneu Danish Cancer Society4 aut |
700 | 1 | a Tumino, Rosario4 aut |
700 | 1 | a van der Schouw, Yvonne T.u University Medical Center Utrecht4 aut |
700 | 1 | a Sharp, Stephen J.u University of Cambridge4 aut |
700 | 1 | a Forouhi, Nita G.u University of Cambridge4 aut |
700 | 1 | a Riboli, Eliou Imperial College London4 aut |
700 | 1 | a McCarthy, Mark I.u Oxford University Hospital,Wellcome Trust Centre for Human Genetics,University of Oxford4 aut |
700 | 1 | a Barroso, Inesu University of Exeter4 aut |
700 | 1 | a Langenberg, Claudiau University of Cambridge4 aut |
700 | 1 | a Wareham, Nicholas J.u University of Cambridge4 aut |
710 | 2 | a University of Cambridgeb Queen Mary University4 org |
773 | 0 | t Scientific Datad : Nature Publishing Groupg 7:1q 7:1x 2052-4463 |
856 | 4 | u https://doi.org/10.1038/s41597-020-00716-7y Fulltext |
856 | 4 | u https://umu.diva-portal.org/smash/get/diva2:1514343/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://www.nature.com/articles/s41597-020-00716-7.pdf |
856 | 4 | u http://dx.doi.org/10.1038/s41597-020-00716-7x freey FULLTEXT |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-178114 |
856 | 4 8 | u https://doi.org/10.1038/s41597-020-00716-7 |
856 | 4 8 | u https://lup.lub.lu.se/record/fef5ff0c-bfc5-43f0-974f-6ec15c6340f2 |
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