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Self-monitoring with home based fecal calprotectin is associated with increased medical treatment : A randomized controlled trial on patients with inflammatory bowel disease

Östlund, Isak (author)
Umeå universitet,Avdelningen för medicin
Werner, Mårten (author)
Umeå universitet,Avdelningen för medicin
Karling, Pontus (author)
Umeå universitet,Avdelningen för medicin
 (creator_code:org_t)
2020-12-07
2021
English.
In: Scandinavian Journal of Gastroenterology. - : Taylor & Francis. - 0036-5521 .- 1502-7708. ; 56:1, s. 38-45
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Objectives: Self-monitoring of inflammatory bowel disease (IBD) with the assistant of telemedicine and home-based fecal calprotectin (FC) tests is evolving in the management of IBD. We performed a randomized controlled trial to investigate the compliance and effects of the model IBD-Home in patients with IBD.Materials and methods: Patients were randomized to IBD-Home + standard care (n = 84) or standard care alone (n = 74). Intervention with IBD-Home included IBDoc FC test kits and a digital application used for answering symptom questionnaires (Abbvie/Telia). They were instructed to use these on demand during a 12-month period. Data was collected retrospectively from medical records. Patients who completed the intervention were phoned and asked to answer a survey about the experience of IBD-Home.Results: The compliance to IBD-Home was low (29%). Women were more compliant compared with men (43% vs 17%, p < .001). A significantly higher proportion of patients in the IBD-Home group increased their medical treatment during the study period in comparison to control subjects (33% vs 15% p = .007) and there was an association between an increase in treatment and compliance to IBD home (multivariate odds ratio 3.22; 95(th) confidence interval 1.04 - 9.95). Overall patients reported a positive experience with slight technical difficulties.Conclusion: Self-monitoring with home based fecal calprotectin and a digital application was found feasible and appreciated by compliers. Compliance to the IBD-Home model was more common in women and associated with an increased treatment for IBD.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)

Keyword

Calprotectin
Crohn's disease
E-health
Inflammatory bowel disease
Self-monitoring
Telemedicine
Ulcerative colitis

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ref (subject category)
art (subject category)

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Östlund, Isak
Werner, Mårten
Karling, Pontus
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MEDICAL AND HEALTH SCIENCES
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Umeå University

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