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Search: onr:"swepub:oai:DiVA.org:umu-181996" > The Functional Foun...

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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004851naa a2200493 4500
001oai:DiVA.org:umu-181996
003SwePub
008210412s2021 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1819962 URI
024a https://doi.org/10.1093/cercor/bhaa3482 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Vidal-Piñeiro, Didacu Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
2451 0a The Functional Foundations of Episodic Memory Remain Stable Throughout the Lifespan
264 c 2020-11-30
264 1b Oxford University Press,c 2021
338 a electronic2 rdacarrier
520 a It has been suggested that specific forms of cognition in older age rely largely on late-life specific mechanisms. Here instead, we tested using task-fMRI (n = 540, age 6-82 years) whether the functional foundations of successful episodic memory encoding adhere to a principle of lifespan continuity, shaped by developmental, structural, and evolutionary influences. We clustered regions of the cerebral cortex according to the shape of the lifespan trajectory of memory activity in each region so that regions showing the same pattern were clustered together. The results revealed that lifespan trajectories of memory encoding function showed a continuity through life but no evidence of age-specific mechanisms such as compensatory patterns. Encoding activity was related to general cognitive abilities and variations of grey matter as captured by a multi-modal independent component analysis, variables reflecting core aspects of cognitive and structural change throughout the lifespan. Furthermore, memory encoding activity aligned to fundamental aspects of brain organization, such as large-scale connectivity and evolutionary cortical expansion gradients. Altogether, we provide novel support for a perspective on memory aging in which maintenance and decay of episodic memory in older age needs to be understood from a comprehensive life-long perspective rather than as a late-life phenomenon only.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Medicinska och farmaceutiska grundvetenskaperx Neurovetenskaper0 (SwePub)301052 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Basic Medicinex Neurosciences0 (SwePub)301052 hsv//eng
653 a aging
653 a development
653 a encoding
653 a fMRI
653 a neuroimaging
700a Sneve, Markus H.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
700a Amlien, Inge K.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
700a Grydeland, Håkonu Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
700a Mowinckel, Athanasia M.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
700a Roe, James M.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
700a Sørensen, Øysteinu Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway4 aut
700a Nyberg, Lars H.,d 1966-u Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Fysiologi,Diagnostisk radiologi4 aut0 (Swepub:umu)lany0001
700a Walhovd, Kristine B.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway4 aut
700a Fjell, Anders M.u Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway4 aut
710a Department of Psychology, Centre for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norwayb Umeå centrum för funktionell hjärnavbildning (UFBI)4 org
773t Cerebral Cortexd : Oxford University Pressg 31:4, s. 2098-2110q 31:4<2098-2110x 1047-3211x 1460-2199
856u https://doi.org/10.1093/cercor/bhaa348y Fulltext
856u https://umu.diva-portal.org/smash/get/diva2:1543667/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print
856u https://academic.oup.com/cercor/article-pdf/31/4/2098/36458471/bhaa348.pdf
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181996
8564 8u https://doi.org/10.1093/cercor/bhaa348

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