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A longitudinal study of lateral ventricle volumes in deficit and non-deficit schizophrenia
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- Hepdurgun, Cenan (author)
- SoCAT Lab, Department of Psychiatry, School of Medicine, Ege University, Izmir, Turkey
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- Karakoc, Gulser (author)
- SoCAT Lab, Department of Psychiatry, School of Medicine, Ege University, Izmir, Turkey
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- Polat, Irmak (author)
- SoCAT Lab, Department of Psychiatry, School of Medicine, Ege University, Izmir, Turkey; Department of Psychiatry, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey
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- (creator_code:org_t)
- Elsevier, 2021
- 2021
- English.
- In: Psychiatry Research. - : Elsevier. - 0925-4927 .- 1872-7506. ; 313
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Although it is generally accepted that negative symptoms of schizophrenia are associated with larger lateral ventricles, this general assumption could not be validated in patients with primary negative symptoms. To elucidate this issue, we conducted a five-year longitudinal study, including deficit (n = 13) and non-deficit (n = 26) schizophrenia patients with healthy controls (n = 18). Analysis with linear mixed effects modeling showed that both the left and the right lateral ventricles of the deficit patients enlarged more than the non-deficit patients. Our results suggest that structural alterations in deficit patients might follow a different trajectory than those in non-deficit patients.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- Follow-up
- Linear mixed effects model
- Primary negative symptoms
- Psychotic disorders
- Structural MRI
Publication and Content Type
- ref (subject category)
- art (subject category)
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- Hepdurgun, Cenan
- Karakoc, Gulser
- Polat, Irmak
- Özalay, Özgun
- Eroglu, Seda
- Erdogan, Yigit
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- Kitis, Omer
- Gonul, Ali Saffe ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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- and Psychiatry
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- Psychiatry Resea ...
- By the university
- Umeå University
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