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Milk Fat Globule Me...
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Hernell, OlleUmeå universitet,Pediatrik
(author)
Milk Fat Globule Membranes : Effects on Microbiome, Metabolome, and Infections in Infants and Children
- Article/chapterEnglish2020
Publisher, publication year, extent ...
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2020-03-16
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S. Karger,2020
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:umu-187590
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-187590URI
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https://doi.org/10.1159/000505066DOI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:kon swepub-publicationtype
Notes
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Dietary supplementation with bovine milk fat globule membrane (MFGM) concentrates has recently emerged as a possible means to improve the health of infants and young children, or defense against infections. We identified 5 double-blind, randomized, controlled trials (DBRCT) exploring the effects of supplementing the diet of infants and children with bovine MFGM concentrates on infections. We reviewed 3 studies which found a protective effect against infections at different ages during infancy and early childhood. Two of them have reported effects on the metabolome, and 1 study also on the microbiome and lipidome. MFGM supplementation had moderate, albeit interesting, effects on the oral and fecal microbiome, fecal and serum/plasma metabolome, and serum and erythrocyte membrane lipidome, which also are reviewed. We conclude that studies on MFGM supplementation during infancy and childhood indicate positive effects on the defense against infections and other outcomes, but more high-quality DBRCTs with well-defined MFGM fractions and outcome measures are needed before firm conclusions can be drawn.
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Lönnerdal, Bo
(author)
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Timby, NiklasUmeå universitet,Pediatrik(Swepub:umu)niti0004
(author)
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Umeå universitetPediatrik
(creator_code:org_t)
Related titles
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In:Milk, Mucosal Immunity and the Microbiome: S. Karger, s. 133-14097833180668529783318066845
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