onr:"swepub:oai:DiVA.org:umu-189516"
Search: onr:"swepub:oai:DiVA.org:umu-189516" > K2S2O8-mediated cou...
- 1 of 1
- Previous record
- Next record
- To hitlist
K2S2O8-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones
-
- Bharate, Jaideep B. (author)
- Umeå universitet,Kemiska institutionen
-
- Ådén, Jörgen, 1980- (author)
- Umeå universitet,Kemiska institutionen
-
- Gharibyan, Anna (author)
- Umeå universitet,Institutionen för medicinsk kemi och biofysik
- show more...
- show less...
- (creator_code:org_t)
- The Royal Society of Chemistry, 2021
- 2021
- English.
- In: Organic and biomolecular chemistry. - : The Royal Society of Chemistry. - 1477-0520 .- 1477-0539. ; 19:44, s. 9758-9772
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- We herein present the synthesis of diversely functionalized pyrimidine fused thiazolino-2-pyridones via K2S2O8-mediated oxidative coupling of 6-amino-7-(aminomethyl)-thiazolino-2-pyridones with aldehydes. The developed protocol is mild, has wide substrate scope, and does not require transition metal catalyst or base. Some of the synthesized compounds have an ability to inhibit the formation of Amyloid-β fibrils associated with Alzheimer's disease, while others bind to mature amyloid-β and α-synuclein fibrils.
Subject headings
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
- Organic and biomolecular chemistry (Search for host publication in LIBRIS)
To the university's database
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Bharate, Jaideep ...
- Ådén, Jörgen, 19 ...
- Gharibyan, Anna
- Adolfsson, Dan E ...
- Jayaweera, Sandu ...
- Singh, Pardeep
- show more...
- Vielfort, Katari ...
- Tyagi, Mohit
- Bonde, Mari
- Bergström, Sven
- Olofsson, Anders ...
- Almqvist, Fredri ...
- show less...
- About the subject
-
- NATURAL SCIENCES
- NATURAL SCIENCES
- and Chemical Science ...
- and Organic Chemistr ...
- Articles in the publication
- Organic and biom ...
- By the university
- Umeå University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
