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  • Gavali, HamidUppsala universitet,Uppsala University,Uppsala Univ, Sweden,Kärlkirurgi (author)

Outcome of Radical Surgical Treatment of Abdominal Aortic Graft and Endograft Infections Comparing Extra-anatomic Bypass with In Situ Reconstruction : A Nationwide Multicentre Study

  • Article/chapterEnglish2021

Publisher, publication year, extent ...

  • Saunders Elsevier,2021
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-189831
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-189831URI
  • https://doi.org/10.1016/j.ejvs.2021.09.033DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-95512URI
  • https://lup.lub.lu.se/record/b7e78df2-5fd3-47d7-a649-30eaebd1b969URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-182080URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459188URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:148391901URI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Objective: Abdominal aortic graft and endograft infection (AGI) is primarily treated by resection of the infected graft and restoration of distal perfusion through extra-anatomic bypass (EAB) or in situ reconstruction/repair (ISR). The aim of this study was to compare these surgical strategies in a nationwide multicentre retrospective cohort study.Methods: The Swedish Vascular Registry (Swedvasc) was used to identify surgically treated abdominal AGIs in Sweden between January 1995 and May 2017. The primary aim was to compare short and long term survival, as well as complications for EAB and ISR.Results: Some 126 radically surgically treated AGI patients were identified – 102 graft infections and 24 endograft infections – treated by EAB: 71 and ISR: 55 (23 neo-aorto-iliac systems, NAISs). No differences in early 30 day (EAB 81.7% vs. ISR 76.4%, p =.46), or long term five year survival (48.2% vs. 49.9%, p =.87) were identified. There was no survival difference comparing NAIS to other ISR strategies. The frequency of recurrent graft infection during follow up was similar: EAB 20.3% vs. ISR 17.0% (p =.56). Survival and re-infection rates of the new conduit did not differ between NAIS and other ISR strategies. Age ≥ 75 years (odds ratio [OR] 4.0, confidence interval [CI] 1.1 – 14.8), coronary artery disease (OR 4.2, CI 1.2 – 15.1) and post-operative circulatory complications (OR 5.2, CI 1.2 – 22.5) were associated with early death. Prolonged antimicrobial therapy (> 3 months) was associated with reduced long term mortality (HR 0.3, CI 0.1 – 0.9).Conclusion: In this nationwide multicentre study comparing outcomes of radically treated AGI, no differences in survival or re-infection rate could be identified comparing EAB and ISR.

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  • Mani, Kevin,1975-Uppsala universitet,Uppsala University,Uppsala Univ, Sweden,Kärlkirurgi(Swepub:uu)kevma940 (author)
  • Furebring, MiaUppsala universitet,Uppsala University,Uppsala Univ, Sweden,Infektionsmedicin(Swepub:uu)miafureb (author)
  • Olsson, Karl Wilhelm,1985-Uppsala universitet,Uppsala University,Uppsala Univ, Sweden,Kärlkirurgi(Swepub:uu)karol118 (author)
  • Lindström, DavidUppsala universitet,Uppsala University,Department of Vascular Surgery, Karolinska University Hospital, Stockholm, Sweden,Uppsala Univ, Sweden; Karolinska Univ Hosp, Sweden,Kärlkirurgi(Swepub:uu)davli314 (author)
  • Sörelius, KarlDepartment of Vascular Surgery, Rigshospitalet, Copenhagen, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Denmark,Copenhagen University Hospital,Rigshosp, Denmark; Univ Copenhagen, Denmark(Swepub:uu)karso162 (author)
  • Sigvant, Birgitta,1962-Uppsala universitet,Uppsala University,Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Örebro University, Örebro, Sweden,Uppsala Univ, Sweden; Orebro Univ, Sweden,Kärlkirurgi(Swepub:uu)birsi511 (author)
  • Gidlund, Khatereh D.Uppsala universitet,Uppsala University,Department of Surgery, Gävle County Hospital, Gävle, Sweden,Uppsala Univ, Sweden; Gavle Cty Hosp, Sweden,Kärlkirurgi(Swepub:uu)khadj328 (author)
  • Torstensson, GustavDepartment of Vascular Surgery, Helsingborg Regional Hospital, Helsingborg, Sweden,Helsingborg Reg Hosp, Sweden(Swepub:lu)gu8201to (author)
  • Andersson, ManneLinköpings universitet,Linköping University,Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden;County Hospital Ryhov, Jönköping County, Department of Surgery, Ryhov, Sweden,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Cty Hosp Ryhov, Sweden(Swepub:liu)manan92 (author)
  • Forssell, ClaesDepartment of Cardiovascular Surgery, Division of Vascular Surgery, Linköping University Hospital, Linköping, Sweden,Region Östergötland, Thorax-kärlkliniken i Östergötland(Swepub:liu)n/a (author)
  • Åstrand, HåkanDepartment of Surgery, County Hospital Ryhov, Jönköping County, Jönköping, Sweden,Cty Hosp Ryhov, Sweden (author)
  • Lundström, TobiasDepartment of Surgery and urology, Eskilstuna Hospital, Eskilstuna, Sweden,Mälar Hospital,Eskilstuna Hosp, Sweden (author)
  • Khan, ShahzadDepartment of Surgery, Malmö University Hospital, Lund University, Malmö, Sweden,Skåne University Hospital,Lund Univ, Sweden (author)
  • Sonesson, BjörnLund University,Lunds universitet,Vaskulära sjukdomar - kliniska studier,Forskargrupper vid Lunds universitet,Vascular Diseases - Clinical Research,Lund University Research Groups,Skåne University Hospital,Lund Univ, Sweden,Department of Surgery, Malmö University Hospital, Lund University, Malmö, Sweden(Swepub:lu)kir-bso (author)
  • Stackelberg, OttoKarolinska Institutet,Karolinska Institute,Department of Clinical Science and Education, Karolinska Institutet, Stockholm, Sweden;Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (author)
  • Gillgren, PeterKarolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Karolinska Inst, Sweden; Soder Sjukhuset, Sweden,Department of Clinical Science and Education, Karolinska Institutet, Stockholm, Sweden;Department of Surgery, Södersjukhuset, Stockholm, Sweden (author)
  • Isaksson, JonUmeå University,Umeå universitet,Kirurgi,Department of Surgical and Peri-operative Sciences, Umeå University, Umeå, Sweden,Umea Univ, Sweden(Swepub:umu)jois0027 (author)
  • Kragsterman, BjörnUppsala universitet,Uppsala University,Västmanland Hospital,Uppsala Univ, Sweden; Vasteras Hosp, Sweden,Kärlkirurgi,Department of Surgery, Västerås Central Hospital, Västerås, Sweden(Swepub:uu)bjkra123 (author)
  • Hörer, Tal M.,1971-Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Cardiothoracic and Vascular Surgery and Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Orebro Univ, Sweden; Orebro Univ, Sweden(Swepub:oru)thr (author)
  • Sadeghi, MitraÖrebro University,Orebro Univ, Sweden; Orebro Univ, Sweden,Department of Cardiothoracic and Vascular Surgery and Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden (author)
  • Wanhainen, AndersUppsala universitet,Uppsala University,Umeå universitet,Kirurgi,Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden,Kärlkirurgi(Swepub:uu)anwan103 (author)
  • Uppsala UniversityUppsala Univ, Sweden (creator_code:org_t)

Related titles

  • In:European Journal of Vascular and Endovascular Surgery: Saunders Elsevier62:6, s. 918-9261078-58841532-2165

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