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A systematic review...
A systematic review of the evidence on the effectiveness and cost-effectiveness of mass screen-and-treat interventions for Malaria control
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- Kim, Sooyoung (author)
- School of Global Public Health, New York University, NY, New York, United States
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- Luande, Verah Nafula (author)
- Umeå universitet,Avdelningen för hållbar hälsa
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- Rocklöv, Joacim, Professor, 1979- (author)
- Umeå universitet,Avdelningen för hållbar hälsa
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- Carlton, Jane M. (author)
- School of Global Public Health, New York University, NY, New York, United States; Center for Genomics and Systems Biology, Department of Biology, New York University, NY, New York, United States
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- Tozan, Yesim (author)
- School of Global Public Health, New York University, NY, New York, United States
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(creator_code:org_t)
- American Society of Tropical Medicine and Hygiene, 2021
- 2021
- English.
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In: American Journal of Tropical Medicine and Hygiene. - : American Society of Tropical Medicine and Hygiene. - 0002-9637 .- 1476-1645. ; 105:6, s. 1722-1731
- Related links:
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https://doi.org/10.4...
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https://umu.diva-por... (primary) (Raw object)
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https://www.ajtmh.or...
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https://urn.kb.se/re...
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https://doi.org/10.4...
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Abstract
Subject headings
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- Malaria elimination and eradication efforts have stalled globally. Further, asymptomatic infections as silent transmission reservoirs are considered a major challenge to malaria elimination efforts. There is increased interest in a mass screen-and-treat (MSAT) strategy as an alternative to mass drug administration to reduce malaria burden and transmission in endemic settings. This study systematically synthesized the existing evidence on MSAT, from both epidemiological and economic perspectives. Searches were conducted on six databases (PubMed, EMBASE, CINALH, Web of Science, Global Health, and Google Scholar) between October and December 2020. Only experimental and quasi-experimental studies assessing the effectiveness and/or cost-effectiveness of MSAT in reducing malaria prevalence or incidence were included. Of the 2,424 citation hits, 14 studies based on 11 intervention trials were eligible. Eight trials were conducted in sub-Saharan Africa and three trials in Asia. While five trials targeted the community as a whole, pregnant women were targeted in five trials, and school children in one trial. Transmission setting, frequency, and timing of MSAT rounds, and measured outcomes varied across studies. The pooled effect size of MSAT in reducing malaria incidence and prevalence was marginal and statistically nonsignificant. Only one study conducted an economic evaluation of the intervention and found it to be cost-effective when compared with the standard of care of no MSAT. We concluded that the evidence for implementing MSAT as part of a routine malaria control program is growing but limited. More research is necessary on its short- and longer-term impacts on clinical malaria and malaria transmission and its economic value.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Publication and Content Type
- ref (subject category)
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