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TUBE project: Trans...
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Martikainen, Maria-ViolaDepartment of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland
(author)
TUBE project: Transport-derived ultrafines and the brain effects
- Article/chapterEnglish2022
Publisher, publication year, extent ...
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2021-12-28
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MDPI,2022
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:umu-190968
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190968URI
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https://doi.org/10.3390/ijerph19010311DOI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The adverse effects of air pollutants on the respiratory and cardiovascular systems are unquestionable. However, in recent years, indications of effects beyond these organ systems have become more evident. Traffic-related air pollution has been linked with neurological diseases, exacerbated cognitive dysfunction, and Alzheimer’s disease. However, the exact air pollutant compositions and exposure scenarios leading to these adverse health effects are not known. Although several components of air pollution may be at play, recent experimental studies point to a key role of ultrafine particles (UFPs). While the importance of UFPs has been recognized, almost nothing is known about the smallest fraction of UFPs, and only >23 nm emissions are regulated in the EU. Moreover, the role of the semivolatile fraction of the emissions has been neglected. The Transport-Derived Ultrafines and the Brain Effects (TUBE) project will increase knowledge on harmful ultrafine air pollutants, as well as semivolatile compounds related to adverse health effects. By including all the major current combustion and emission control technologies, the TUBE project aims to provide new information on the adverse health effects of current traffic, as well as information for decision makers to develop more effective emission legislation. Most importantly, the TUBE project will include adverse health effects beyond the respiratory system; TUBE will assess how air pollution affects the brain and how air pollution particles might be removed from the brain. The purpose of this report is to describe the TUBE project, its background, and its goals.
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Aakko-Saksa, PäiviVTT Technical Research Centre of Finland Ltd., Espoo, Finland
(author)
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Broek, Lenie van denMimetas BV, Oegstgeest, Netherlands
(author)
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Cassee, Flemming R.Centre for Sustainability, Environment and Health, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands; Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands
(author)
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Carare, Roxana O.Faculty of Medicine, University of Southampton, Southampton, United Kingdom
(author)
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Chew, SweelinA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
(author)
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Dinnyes, AndrasBiotalentum Ltd., Godollo, Hungary
(author)
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Giugno, RosalbaComputer Science Department, University of Verona, Verona, Italy
(author)
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Kanninen, Katja M.A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
(author)
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Malm, TarjaA.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
(author)
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Muala, AlaUmeå universitet,Avdelningen för medicin(Swepub:umu)almu0002
(author)
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Nedergaard, MaikenCenter for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
(author)
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Oudin, AnnaUmeå universitet,Avdelningen för medicin(Swepub:umu)anou0004
(author)
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Oyola, PedroCentro Mario Molina Chile, Strategic Studies Department, Santiago, Chile
(author)
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Pfeiffer, Tobias V.VSParticle B.V., Delft, Netherlands
(author)
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Rönkkö, TopiAerosol Physics Laboratory, Physics Unit, Faculty of Engineering and Natural Sciences, Tampere University, Tampere, Finland
(author)
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Saarikoski, SannaAtmospheric Composition Research, Finnish Meteorological Institute, Helsinki, Finland
(author)
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Sandström, Thomas,1957-Umeå universitet,Avdelningen för medicin(Swepub:umu)thsa0001
(author)
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Schins, Roel P.F.IUF—Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany
(author)
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Topinka, JanDepartment of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine of the CAS, Videnska 1083, Prague, Czech Republic
(author)
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Yang, MoDepartment of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland
(author)
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Zeng, XiaowenGuangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, China
(author)
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Westerink, Remco H.S.Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands
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Jalava, Pasi I.Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland
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Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, FinlandVTT Technical Research Centre of Finland Ltd., Espoo, Finland
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In:International Journal of Environmental Research and Public Health: MDPI19:11661-78271660-4601
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Martikainen, Mar ...
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Aakko-Saksa, Päi ...
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Broek, Lenie van ...
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Carare, Roxana O ...
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Chew, Sweelin
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Dinnyes, Andras
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Giugno, Rosalba
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Rönkkö, Topi
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Saarikoski, Sann ...
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Schins, Roel P.F ...
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