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Critical appraisal ...
Critical appraisal trumps timing of antihypertensive medications : [Studie avfärdar fördelar med blodtryckssänkande till natten]
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- Brunström, Mattias (author)
- Umeå universitet,Avdelningen för medicin
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- Svensson, Per (author)
- VO kardiologi, Södersjukhuset; Institutionen för klinisk forskning och utbildning, Södersjukhuset, Karolinska institutet, Stockholm
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(creator_code:org_t)
- Läkartidningen Förlag AB, 2022
- 2022
- English.
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In: Läkartidningen. - : Läkartidningen Förlag AB. - 0023-7205 .- 1652-7518. ; 119
- Related links:
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https://lakartidning...
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Abstract
Subject headings
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- Treatment In Morning versus Evening (TIME) was a pragmatic randomized controlled trial, including more than 21 000 people with medically treated hypertension. Participants were randomized to morning or evening intake of their antihypertensive medications and followed for an average of 5.2 years. Results were completely neutral, as opposed to the heavily criticized Hygia trial published in 2019. These findings are of clinical importance because they show that it does not matter if patients take their antihypertensive medications in the morning or evening. They are also of general scientific interest because they highlight the importance of post publication peer review and the need for replication of surprising scientific findings.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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