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Left atrial contrac...
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Gottfridsson, PeterUmeå universitet,Anestesiologi och intensivvård
(author)
Left atrial contraction strain during a Valsalva manoeuvre : A study in healthy humans
- Article/chapterEnglish2023
Publisher, publication year, extent ...
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2022-12-27
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John Wiley & Sons,2023
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electronicrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:umu-202113
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-202113URI
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https://doi.org/10.1111/cpf.12806DOI
Supplementary language notes
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Language:English
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Summary in:English
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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BACKGROUND: Cardiac mechanics are influenced by loading conditions as well as sympathetic tone. Left atrial (LA) contractile function assessed by two-dimensional (2D) strain has been described in the setting of controlled preload alterations; however, studies show conflicting findings about change or direction of change. We hypothesized that the controlled preload reduction and the sympathetic nervous system activation that occurs during a standardized Valsalva manoeuvre would bring about a change in LA contraction strain.aMETHODS: Healthy young adults of both sexes were recruited. Transthoracic echocardiographic ultrasound images were collected before and during a Valsalva manoeuvre. Standard imaging windows for LA strain assessment were used and the images were copied and stored for later offline analysis. These were assessed for adequate atrial wall visualization in 2D strain assessment. Paired comparisons were carried out using Student's T test.RESULT: Thirty-eight participants were included and there were 22 complete studies with paired pre- and during Valsalva manoeuvre. LA contraction strain at baseline was 10.5 ± 2.8% (standard deviation) and during the Valsalva manoeuvre 10.6 ± 4.6%, p = 0.86.CONCLUSION: The Valsalva manoeuvre, a combination of preload reduction and sympathetic nervous system activation, seems not to be associated with a change in LA contraction strain in healthy young individuals. LA contraction strain should be interpreted in the context of both atrial loading conditions and prevailing autonomic nervous system activity.
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Law, LucyUmeå universitet,Klinisk fysiologi(Swepub:umu)lula0018
(author)
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Aroch, RomanUmeå universitet,Anestesiologi och intensivvård(Swepub:umu)roaa0001
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Myrberg, TomiUmeå universitet,Anestesiologi och intensivvård(Swepub:umu)topo0002
(author)
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Hultin, Magnus,1968-Umeå universitet,Anestesiologi och intensivvård(Swepub:umu)mahu0016
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Lindqvist, PerUmeå universitet,Klinisk fysiologi(Swepub:umu)peli0011
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Haney, MichaelUmeå universitet,Anestesiologi och intensivvård(Swepub:umu)milhay96
(author)
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Umeå universitetAnestesiologi och intensivvård
(creator_code:org_t)
Related titles
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In:Clinical Physiology and Functional Imaging: John Wiley & Sons43:3, s. 165-1691475-09611475-097X
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