Left atrial remodeling in response to aortic valve replacement: pathophysiology and myocardial strain analysis

Left atrial remodeling in response to aortic valve replacement : pathophysiology and myocardial strain analysis

Lisi, Matteo, 1982- (author): Umeå universitet,Kardiologi,Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy; Department of Cardiovascular Disease—AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Ravenna, Italy

Pastore, Maria Concetta (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

Fiorio, Alessio (author): Department of Cardiovascular Disease—AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Ravenna, Italy; Cardiology Unit and LTTA Centre, University of Ferrara, Ferrara, Italy

Cameli, Matteo (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

Mandoli, Giulia Elena (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

Righini, Francesca Maria (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

Cavigli, Luna (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

D’Ascenzi, Flavio (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

Focardi, Marta (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

Rubboli, Andrea (author): Department of Cardiovascular Disease—AUSL Romagna, Division of Cardiology, Ospedale S. Maria Delle Croci, Ravenna, Italy

Campo, Gianluca (author): Cardiology Unit and LTTA Centre, University of Ferrara, Ferrara, Italy

Mondillo, Sergio (author): Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy

(creator_code:org_t)

Related links:: https://doi.org/10.3...; show more...; https://umu.diva-por... (primary) (Raw object); https://urn.kb.se/re...; https://doi.org/10.3...; show less...

Abstract Subject headings

Severe aortic stenosis (AS) is the most common valve disease in the elderly and is associated with poor prognosis if treated only medically. AS causes chronic pressure overload, concentric left ventricular (LV) hypertrophy, myocardial stiffness, and diastolic dysfunction. This adverse remodeling also affects the left atrium (LA), which dilates and develops myocardial fibrosis, with a reduction in intrinsic function and a consequent high risk of the development of atrial fibrillation. Speckle-tracking echocardiography is able to detect myocardial dysfunction before other conventional parameters, such as LV ejection fraction, and also predict clinical outcomes. This review aims at describing LV and LA remodeling in AS and before and after aortic valve replacement and the usefulness of myocardial strain analysis in this clinical setting.

By the author/editor: Lisi, Matteo, 19 ...; Pastore, Maria C ...; Fiorio, Alessio; Cameli, Matteo; Mandoli, Giulia ...; Righini, Frances ...; show more...; Cavigli, Luna; D’Ascenzi, Flavi ...; Focardi, Marta; Rubboli, Andrea; Campo, Gianluca; Mondillo, Sergio; Henein, Michael ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

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