Search: onr:"swepub:oai:DiVA.org:umu-204476" >
-
Nyman, EmmaUmeå universitet,Institutionen för folkhälsa och klinisk medicin
(author)
Carotid wall echogenicity at baseline associates with accelerated vascular aging in a middle-aged population
- Article/chapterEnglish2023
Publisher, publication year, extent ...
-
2023-01-21
-
Springer Science+Business Media B.V.2023
-
electronicrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:umu-204476
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204476URI
-
https://doi.org/10.1007/s10554-022-02760-3DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Ultrasonic echolucent carotid intima-media (IM) complex and accelerated progression of carotid intima mediathickness (cIMT) have both separately been shown to predict future cardiovascular events. The aim of this studywas to evaluate if the echogenicity of the IM-complex is associated with the 3-year progression of cIMT. B-modeultrasound images captured at baseline and 3-year follow-up in the ‘Visualization of asymptomatic atherosclerotic disease for optimum cardiovascular prevention’ (VIPVIZA) trial were included (n: 3154). The bilateral mean cIMT and IM-echogenicity by greyscale median (GSM) were measured in the common carotid artery. Associations between IM-GSM at baseline and the 3-year cIMT progression were investigated using linear regression models for the whole population and stratified by sex, age and VIPVIZA study group (intervention versus control). In addition, adjusted analyses for confounding factors were performed. Unadjusted analysis showed that decreased IM-GSM at baseline was associated with increased progression of cIMT (p < 0.001). Stratified by age, the association was significant among 40 (p < 0.001) and 60 years old (p < 0.001). The association was statistically significant in both sexes and on comparison of VIPVIZA study subgroups. Adjustments for confounding factors did not alter the estimated relationship between IM-GSM and cIMT progression. Echolucent carotid intima media at baseline associates with increased 3-year cIMT progression among an asymptomatic, middle-aged population. Echogenicity of the intima media may identify individuals at risk for accelerated vascular aging.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Liv, Per,1979-Umeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)perliv00
(author)
-
Wester, Per,1959-Umeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)pewe0002
(author)
-
Näslund, UlfUmeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)ulna0002
(author)
-
Grönlund, ChristerUmeå universitet,Radiofysik(Swepub:umu)chgr0009
(author)
-
Umeå universitetInstitutionen för folkhälsa och klinisk medicin
(creator_code:org_t)
Related titles
-
In:The International Journal of Cardiovascular Imaging: Springer Science+Business Media B.V.39:3, s. 575-5831569-57941875-8312
Internet link
To the university's database