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Cognitive and motor...
Cognitive and motor decline in dementia with lewy bodies and Parkinson's disease dementia
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- Gonzalez, Maria Camila (author)
- Department of Quality and Health Technology, Faculty of Health Sciences, University of Stavanger, Stavanger, Norway; The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway; Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway
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- Tovar-Rios, Diego Alejandro (author)
- Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway; Grupos de investigación INFERIR and PRECEC, Section of Biostatistics, Universidad del Valle, Santiago de Cali, Colombia
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- Alves, Guido (author)
- The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway; Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway; Department of Neurology, Stavanger University Hospital, Stavanger, Norway
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- Dalen, Ingvild (author)
- Department of Neurology, Stavanger University Hospital, Stavanger, Norway
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- Williams-Gray, Caroline H. (author)
- Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom
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- Camacho, Marta (author)
- Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom
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- Forsgren, Lars (author)
- Umeå universitet,Neurovetenskaper
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- Bäckström, David C, M.D. 1978- (author)
- Umeå universitet,Neurovetenskaper
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- Lawson, Rachael A. (author)
- Translational and Clinical Research Institute, Newcastle University, Tyne, United Kingdom
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- Macleod, Angus D. (author)
- Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom
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- Counsell, Carl E. (author)
- Institute of Applied Health Sciences, University of Aberdeen, Polwarth Building, Aberdeen, United Kingdom
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- Paquet, Claire (author)
- Université de Paris, Cognitive Neurology Center, APHP, Lariboisière Fernand-Widal Hospital, Paris, France
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- DeLena, Carlo (author)
- Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy
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- D'Antonio, Fabrizia (author)
- Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy
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- Pilotto, Andrea (author)
- Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
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- Padovani, Alessandro (author)
- Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy
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- Blanc, Frédéric (author)
- Memory Resource and Research Centre (CM2R), Geriatrics Day Hospital, Geriatrics Department, University Hospital of Strasbourg, Strasbourg Cedex, France
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- Falup-Pecurariu, Cristian (author)
- Department of Neurology, County Clinic Hospital, Faculty of Medicine, Transilvania University, Brasov, Romania
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- Lewis, Simon J.G. (author)
- The University of Sydney, Camperdown, Australia
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- Rejdak, Konrad (author)
- Department of Neurology, Medical University of Lublin, Lublin, Poland
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- Papuc, Ewa (author)
- Department of Neurology, Medical University of Lublin, Lublin, Poland
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- Hort, Jakub (author)
- Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic
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- Nedelska, Zuzana (author)
- Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic
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- O'Brien, John (author)
- Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom
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- Bonanni, Laura (author)
- Department of Medicine and Aging Sciences, University Gd'Annunzio of Chieti-Pescara, Chieti, Italy
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- Marquié, Marta (author)
- Ace Alzheimer Center Barcelona—Universitat Internacional de Catalunya, Barcelona, Spain
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- Boada, Mercè (author)
- Ace Alzheimer Center Barcelona—Universitat Internacional de Catalunya, Barcelona, Spain
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- Pytel, Vanesa (author)
- Ace Alzheimer Center Barcelona—Universitat Internacional de Catalunya, Barcelona, Spain
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- Abdelnour, Carla (author)
- Department of Neurology and Neurological Sciences, Stanford University School of Medicine, CA, Stanford, United States
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- Alcolea, Daniel (author)
- Sant Pau Memory Unit, Department of Neurology, IIB Sant Pau—Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain
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- Beyer, Katrin (author)
- Department Neuroscience, Research Institute Germans Trias i Pujol, Badalona, Spain
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- Tysnes, Ole-Bjørn (author)
- Department of Neurology, Haukeland University Hospital, Bergen, Norway
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- Aarsland, Dag (author)
- Karolinska Institutet
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- Maple-Grødem, Jodi (author)
- The Norwegian Centre for Movement Disorders, Stavanger University Hospital, Stavanger, Norway; Department of Chemistry, Bioscience and Environmental Engineering, University of Stavanger, Stavanger, Norway
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(creator_code:org_t)
- John Wiley & Sons, 2023
- 2023
- English.
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In: Movement Disorders Clinical Practice. - : John Wiley & Sons. - 2330-1619. ; 10:6, s. 980-986
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Background: There is a need to better understand the rate of cognitive and motor decline of Dementia with Lewy bodies (DLB) and Parkinson's disease Dementia (PDD).Objectives: To compare the rate of cognitive and motor decline in patients with DLB and PDD from the E-DLB Consortium and the Parkinson's Incidence Cohorts Collaboration (PICC) Cohorts.Methods: The annual change in MMSE and MDS-UPDRS part III was estimated using linear mixed regression models in patients with at least one follow-up (DLB n = 837 and PDD n = 157).Results: When adjusting for confounders, we found no difference in the annual change in MMSE between DLB and PDD (−1.8 [95% CI −2.3, −1.3] vs. −1.9 [95% CI −2.6, −1.2] [P = 0.74]). MDS-UPDRS part III showed nearly identical annual changes (DLB 4.8 [95% CI 2.1, 7.5]) (PDD 4.8 [95% CI 2.7, 6.9], [P = 0.98]).Conclusions: DLB and PDD showed similar rates of cognitive and motor decline. This is relevant for future clinical trial designs.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Keyword
- dementia with Lewy bodies
- international cohort
- Parkinson's disease dementia
- parkinsonism
- rate of cognitive decline
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Gonzalez, Maria ...
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Tovar-Rios, Dieg ...
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Alves, Guido
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Dalen, Ingvild
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Williams-Gray, C ...
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Camacho, Marta
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show more...
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Forsgren, Lars
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Bäckström, David ...
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Lawson, Rachael ...
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Macleod, Angus D ...
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Counsell, Carl E ...
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Paquet, Claire
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DeLena, Carlo
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D'Antonio, Fabri ...
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Pilotto, Andrea
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Padovani, Alessa ...
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Blanc, Frédéric
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Falup-Pecurariu, ...
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Lewis, Simon J.G ...
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Rejdak, Konrad
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Papuc, Ewa
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Hort, Jakub
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Nedelska, Zuzana
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O'Brien, John
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Bonanni, Laura
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Marquié, Marta
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Boada, Mercè
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Pytel, Vanesa
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Abdelnour, Carla
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Alcolea, Daniel
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Beyer, Katrin
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Tysnes, Ole-Bjør ...
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Aarsland, Dag
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Maple-Grødem, Jo ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Neurology
- Articles in the publication
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Movement Disorde ...
- By the university
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Umeå University
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Karolinska Institutet