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Promoting healthy populations as a pandemic preparedness strategy : a simulation study from Mexico

Johnson, Rob (author)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute for Disease and Emergency Analytics, Imperial College London, United Kingdom
Carnalla, Martha (author)
Centro de Salud en Investigación Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico
Basto-Abreu, Ana (author)
Centro de Salud en Investigación Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico
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Haw, David (author)
Department of Mathematical Sciences and Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, United Kingdom
Morgenstern, Christian (author)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute for Disease and Emergency Analytics, Imperial College London, United Kingdom
Doohan, Patrick (author)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute for Disease and Emergency Analytics, Imperial College London, United Kingdom
Forchini, Giovanni (author)
Umeå universitet,Handelshögskolan vid Umeå universitet,MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute for Disease and Emergency Analytics, Imperial College London, United Kingdom
Hauck, Katharina D. (author)
MRC Centre for Global Infectious Disease Analysis & WHO Collaborating Centre for Infectious Disease Modelling, Jameel Institute for Disease and Emergency Analytics, Imperial College London, United Kingdom
Barrientos-Gutiérrez, Tonatiuh (author)
Centro de Salud en Investigación Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico
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 (creator_code:org_t)
Elsevier, 2024
2024
English.
In: Lancet Regional Health - Americas. - : Elsevier. - 2667-193X. ; 30
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Background: The underlying health status of populations was a major determinant of the impact of the COVID-19 pandemic, particularly obesity prevalence. Mexico was one of the most severely affected countries during the COVID-19 pandemic and its obesity prevalence is among the highest in the world. It is unknown by how much the COVID-19 burden could have been reduced if systemic actions had been implemented to reduce excess weight in Mexico before the onset of the pandemic.Methods: Using a dynamic epidemic model based on nationwide data, we compare actual deaths with those under hypothetical scenarios assuming a lower body mass index in the Mexican population, as observed historically. We also model the number of deaths that would have been averted due to earlier implementation of front-of-pack warning labels or due to increases in taxes on sugar-sweetened beverages and non-essential high-energy foods in Mexico.Findings: We estimate that 52.5% (95% prediction interval (PI) 43.2, 61.6%) of COVID-19 deaths were attributable to obesity for adults aged 20–64 and 23.8% (95% PI 18.7, 29.1%) for those aged 65 and over. Had the population BMI distribution remained as it was in 2000, 2006, or 2012, COVID-19 deaths would have been reduced by an expected 20.6% (95% PI 16.9, 24.6%), 9.9% (95% PI 7.3, 12.9%), or 6.9% (95% PI 4.5, 9.5%), respectively. If the food-labelling intervention introduced in 2020 had been introduced in 2018, an expected 6.2% (95% PI 5.2, 7.3%) of COVID-19 deaths would have been averted. If taxes on sugar-sweetened beverages and high-energy foods had been doubled, trebled, or quadrupled in 2018, COVID-19 deaths would have been reduced by an expected 4.1% (95% PI 2.5, 5.7%), 7.9% (95% PI 4.9, 11.0%), or 11.6% (95% PI 7.3, 15.8%), respectively.Interpretation: Public health interventions targeting underlying population health, including non-communicable chronic diseases, is a promising line of action for pandemic preparedness that should be included in all pandemic plans.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Keyword

BMI
COVID-19
Epidemic response plan
Obesity
Pandemic preparedness
Population health

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ref (subject category)
art (subject category)

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