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Temporal gut microb...
Temporal gut microbiota variability and association with dietary patterns : from the one-year observational Diet, cancer, and health - Next generations MAX study
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- Rostgaard-Hansen, Agnetha, 1986 (author)
- Division of Food and Nutrition Science, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden,Chalmers tekniska högskola,Chalmers University of Technology
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- Esberg, Anders (author)
- Umeå universitet,Institutionen för odontologi,Umeå University
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- Dicksved, Johan (author)
- Department of Animal Nutrition and Management, Swedish University of Agricultural Sciences, Uppsala, Sweden,Sveriges lantbruksuniversitet (SLU),Swedish University of Agricultural Sciences (SLU)
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- Hansen, Torben (author)
- Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark,Novo Nordisk Fonden,Novo Nordisk Foundation
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- Pelve, Erik (author)
- Department of Anatomy, Physiology and Biochemistry, Swedish University of Agricultural Sciences, Uppsala, Sweden,Sveriges lantbruksuniversitet (SLU),Swedish University of Agricultural Sciences (SLU)
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- Brunius, Carl, 1974 (author)
- Division of Food and Nutrition Science, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden,Chalmers tekniska högskola,Chalmers University of Technology
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- Halkjær, Jytte (author)
- Danish Cancer Research Society Center, Denmark
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- Tjønneland, Anne (author)
- Department of Public Health, University of Copenhagen, Copenhagen, Denmark,Köpenhamns universitet,University of Copenhagen
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- Johansson, Ingegerd (author)
- Umeå universitet,Institutionen för odontologi,Umeå University
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- Landberg, Rikard, 1981 (author)
- Division of Food and Nutrition Science, Department of Life Sciences, Chalmers University of Technology, Gothenburg, Sweden,Chalmers tekniska högskola,Chalmers University of Technology
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(creator_code:org_t)
- Elsevier, 2024
- 2024
- English.
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In: American Journal of Clinical Nutrition. - : Elsevier. - 0002-9165 .- 1938-3207. ; 119:4, s. 1015-1026
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Background: Knowledge about the variability of gut microbiota within an individual over time is important to allow meaningful investigations of the gut microbiota in relation to diet and health outcomes in observational studies. Plant-based dietary patterns have been associated with a lower risk of morbidity and mortality and may alter gut microbiota in a favorable direction.Objectives: To assess the gut microbiota variability during one year and investigate the association between adherence to diet indexes and the gut microbiota in a Danish population.Methods: Four hundred forty-four participants were included in the Diet, Cancer, and Health - Next Generations MAX study (DCH-NG MAX). Stool samples collected up to three times during a year were analyzed by 16S ribosomal ribonucleic acid gene sequencing. Diet was obtained by 24-hour dietary recalls. Intraclass correlation coefficient (ICC) was calculated to assess temporal microbial variability based on 214 individuals. Diet indexes (Nordic, Mediterranean, and plant-based diets) and food groups thereof were associated with gut microbiota using linear regression analyses.Results: We found that 91 out of 234 genera had an ICC >0.5. We identified three subgroups dominated by Bacteroides, Prevotella 9, and Ruminococcaceae and adherence to diet indexes differed between subgroups. Higher adherence to diet indexes was associated with the relative abundance of 22 genera. Across diet indexes, higher intakes of fruit, vegetables, whole grains/cereals, and nuts were most frequently associated with these genera.Conclusions: In the DCH-NG MAX study, 39% of the genera had an ICC >0.5 over one year, suggesting that these genera could be studied with health outcomes in prospective analyses with acceptable precision. Adherence to the Nordic, Mediterranean, and plant-based diets differed between bacterial subgroups and was associated with a higher abundance of genera with fiber-degrading properties. Fruits, vegetables, whole grains/cereals, and nuts were frequently associated with these genera.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- dietary patterns
- epidemiology
- healthy Nordic food index
- healthy plant-based diet index
- human gut microbiota
- plant-based diet index
- provegetarian diet index
- relative Mediterranean diet score
- temporal variability
- unhealthy plant-based diet index
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Rostgaard-Hansen ...
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Esberg, Anders
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Dicksved, Johan
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Hansen, Torben
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Pelve, Erik
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Brunius, Carl, 1 ...
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Halkjær, Jytte
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Tjønneland, Anne
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Johansson, Ingeg ...
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Landberg, Rikard ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Nutrition and Di ...
- Articles in the publication
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American Journal ...
- By the university
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Umeå University
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Chalmers University of Technology