Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study

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Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study

Ahti, Johan (author): Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Finland

Kieseppä, Tuula (author): Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Finland; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland

Suvisaari, Jaana (author): Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland

Suokas, Kimmo (author): Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland; Tampere University Hospital, Tampere, Finland; Department of Psychiatry, Pirkanmaa Hospital District, Tampere, Finland

Holm, Minna (author): Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Wegelius, Asko (author): Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Finland; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland; Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland

Ahola-Olli, Ari (author): Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland; Stanley Center for Psychiatric Research, The Broad Institute of MIT (Massachusetts Institute of Technology) and Harvard, MA, Cambridge, United States; Analytical and Translational Genetics Unit, Massachusetts General Hospital, MA, Boston, United States

Häkkinen, Katja (author): Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio, Finland

Kampman, Olli (author): Tampere University Hospital, Tampere, Finland; Department of Psychiatry, Pirkanmaa Hospital District, Tampere, Finland; Department of Psychiatry, Pirkanmaa Hospital District, Tampere, Finland

Lähteenvuo, Markku (author): Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio, Finland

Paunio, Tiina (author): Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Finland; Mental Health Unit, Finnish Institute for Health and Welfare, Helsinki, Finland

Tiihonen, Jari (author): Karolinska Institutet,Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Forensic Psychiatry, Niuvanniemi Hospital, University of Eastern Finland, Kuopio, Finland; Center for Psychiatry Research, Stockholm City Council, Stockholm, Sweden

Tuulio-Henriksson, Annamari (author): Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland

Isometsä, Erkki (author): Department of Psychiatry, University of Helsinki and Helsinki University Hospital, Finland

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Elsevier, 2022
2022
English.
In: Schizophrenia Research. - : Elsevier. - 0920-9964 .- 1573-2509. ; 244, s. 10-17

Related links:: https://doi.org/10.1...; show more...; https://urn.kb.se/re...; https://doi.org/10.1...; http://kipublication...; show less...

Journal article (peer-reviewed)

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Background: Psychotic disorders differ in their impact on psychosocial functioning. However, few studies have directly compared psychosocial functioning and its determinants between schizophrenia, schizoaffective disorder (SAD), bipolar disorder (BD), and major depressive disorder with psychotic features (psychotic MDD). Objective: We compared rates of independent living, employment, marriage, and having children between these diagnostic groups in a large national sample of participants with psychotic disorders in Finland.Methods: A cross-sectional substudy of participants (N = 9148) aged 18 to 65 years in the Finnish SUPER study, recruited nationwide from health- and social care settings and with advertisements. Psychosis diagnoses, age of onset, and hospitalizations were collected from healthcare registers. Participants were interviewed for psychosocial functioning. Associations of age of onset, hospitalizations, gender, and education with psychosocial functioning were analyzed using logistic regression models.Results: Of participants, 13.8% were employed or studying, 72.0% living independently and 32.5% had children. Overall, BD was associated with best, SAD and psychotic MDD with intermediate, and schizophrenia with worst level of psychosocial functioning. Greatest differences were found in independent living (OR 4.06 for BD vs. schizophrenia). In multivariate models, gender and number of hospitalizations predicted employment, marriage, and independent living in all diagnostic categories, and age of onset in some diagnostic categories.Conclusions: Level of functioning and psychosocial outcomes differed markedly between psychotic disorders, particularly in independent living. Outcomes were worst for schizophrenia and best for BD. Across all psychotic disorders, female gender and lifetime number of hospitalizations had strong independent associations with marriage, employment, and independent living.

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By the author/editor: Ahti, Johan; Kieseppä, Tuula; Suvisaari, Jaana; Suokas, Kimmo; Holm, Minna; Wegelius, Asko; show more...; Ahola-Olli, Ari; Häkkinen, Katja; Kampman, Olli; Lähteenvuo, Mark ...; Paunio, Tiina; Tiihonen, Jari; Tuulio-Henriksso ...; Isometsä, Erkki; show less...

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MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

Articles in the publication: Schizophrenia Re ...

By the university: Umeå University; Karolinska Institutet

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Differences in psychosocial functioning between psychotic disorders in the Finnish SUPER study

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