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Six-month prostate ...
Six-month prostate cancer empowerment program (PC-PEP) improves urinary function : a randomized trial
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- Lawen, Tarek (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Ilie, Gabriela (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada; Department of Radiation Oncology, Dalhousie University, NS, Halifax, Canada; Department of Community Health and Epidemiology, Dalhousie University, NS, Halifax, Canada
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- Mason, Ross (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Rendon, Ricardo (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Spooner, Jesse (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Champion, Emmi (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Davis, Jessica (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- MacDonald, Cody (author)
- Department of Community Health and Epidemiology, Dalhousie University, NS, Halifax, Canada
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- Kucharczyk, Michael J. (author)
- Department of Oncology, Queens University, ON, Kingston, Canada
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- Patil, Nikhilesh (author)
- Department of Radiation Oncology, Dalhousie University, NS, Halifax, Canada
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- Bowes, David (author)
- Department of Radiation Oncology, Dalhousie University, NS, Halifax, Canada
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- Bailly, Greg (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Bell, David (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Lawen, Joseph (author)
- Department of Urology, Dalhousie University, NS, Halifax, Canada
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- Wilke, Derek (author)
- Department of Radiation Oncology, Dalhousie University, NS, Halifax, Canada
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- Kephart, George (author)
- Umeå universitet,Institutionen för omvårdnad,Department of Community Health and Epidemiology, Dalhousie University, NS, Halifax, Canada; School of Health Administration, Dalhousie University, NS, Halifax, Canada
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- Rutledge, Robert David Harold (author)
- Department of Radiation Oncology, Dalhousie University, NS, Halifax, Canada
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(creator_code:org_t)
- MDPI, 2024
- 2024
- English.
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In: Cancers. - : MDPI. - 2072-6694. ; 16:5
- Related links:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Subject headings
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- Purpose: This is a secondary analysis examining a six-month home-based Prostate Cancer-Patient Empowerment Program (PC-PEP) on patient-reported urinary, bowel, sexual, and hormonal function in men with curative prostate cancer (PC) against standard of care.Methods: In a crossover clinical trial, 128 men scheduled for PC surgery (n = 62) or radiotherapy with/without hormones (n = 66) were randomized to PC-PEP (n = 66) or waitlist-control and received the standard of care for 6 months, and then PC-PEP to the end of the year. PC-PEP included daily emails with video instructions, aerobic and strength training, dietary guidance, stress management, and social support, with an initial PFMT nurse consultation. Over 6 months, participants in the PC-PEP received optional text alerts (up to three times daily) reminding them to follow the PFMT video program, encompassing relaxation, quick-twitch, and endurance exercises; compliance was assessed weekly. Participants completed baseline, 6, and 12-month International Prostate Symptom Score (IPSS) and Expanded Prostate Cancer Index Composite (EPIC) questionnaires.Results: At 6 months, men in the PC-PEP reported improved urinary bother (IPSS, p = 0.004), continence (EPIC, p < 0.001), and irritation/obstruction function (p = 0.008) compared to controls, with sustained urinary continence benefits at 12 months (p = 0.002). Surgery patients in the waitlist-control group had 3.5 (95% CI: 1.2, 10, p = 0.024) times and 2.3 (95% CI: 0.82, 6.7, p = 0.11) times higher odds of moderate to severe urinary problems compared to PC-PEP at 6 and 12 months, respectively.Conclusions: PC-PEP significantly improves lower urinary tract symptoms, affirming its suitability for clinical integration alongside established mental health benefits in men with curative prostate cancer.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
Keyword
- behavioural intervention
- cancer survivorship
- eHealth
- erectile dysfunction
- incontinence
- patient education and activation
- pelvic floor muscle training (PFMT)
- prostate cancer
- sexual function
- urinary function
Publication and Content Type
- ref (subject category)
- art (subject category)
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Cancers
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To the university's database
- By the author/editor
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Lawen, Tarek
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Ilie, Gabriela
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Mason, Ross
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Rendon, Ricardo
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Spooner, Jesse
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Champion, Emmi
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Davis, Jessica
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MacDonald, Cody
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Kucharczyk, Mich ...
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Patil, Nikhilesh
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Bowes, David
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Bailly, Greg
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Bell, David
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Lawen, Joseph
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Wilke, Derek
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Kephart, George
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Rutledge, Robert ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Urology and Neph ...
- Articles in the publication
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Cancers
- By the university
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Umeå University