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Guidelines for comp...
Guidelines for composing and assessing a paper on the treatment of pain : A practical application of evidence-based medicine principles to a cost-effectiveness analysis of the MINT randomized clinical trials
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- Ehsanian, Reza (author)
- Division of Physical Medicine & Rehabilitation, Department of Orthopaedics & Rehabilitation, University of New Mexico School of Medicine, NM, Albuquerque, United States
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- Malone, Daniel C. (author)
- Department of Pharmacotherapy, University of Utah, UT, Salt Lake City, United States
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- Hambraeus, Johan (author)
- Umeå universitet,Institutionen för epidemiologi och global hälsa,Smartkliniken Eques Indolor, Vallentuna, Sweden
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- Monteiro, Pedro M. (author)
- Department of Neurosurgery, Centro Hospitalar e Universitário de Coimbra (CHUC), Porto, Portugal
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- Hodde, Michael (author)
- Department of Physical Medicine & Rehabilitation, University of Pennsylvania Perelman School of Medicine, PA, Philadelphia, United States
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- Lee, David (author)
- Fullerton Orthopedic Surgery Medical Group, Fullerton, CA, United States
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- McKenna, Michael (author)
- Michael J. McKenna, MDPC, NV, Las Vegas, United States
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- Wahezi, Sayed E. (author)
- Department of Rehabilitation Medicine and Multidisciplinary Pain Program at Montefiore Medical Center, NY, Bronx, United States
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- McCormick, Zachary L. (author)
- Department of Physical Medicine and Rehabilitation, University of Utah School of Medicine, UT, Salt Lake City, United States
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- Duszynski, Belinda (author)
- Spine Intervention Society, Hinsdale, IL, United States
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- Cheng, David S. (author)
- Department of Neurological Surgery, University of Southern California, CA, Los Angeles, United States
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(creator_code:org_t)
- Elsevier, 2022
- 2022
- English.
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In: Interventional Pain Medicine. - : Elsevier. - 2772-5944. ; 1:1
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Abstract
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- Objective: Apply established principles of evidence-based medicine to the interpretation of the cost-effectiveness analysis related to the MINT Randomized Clinical Trials (RCTs).Design: EditorialMethods: Spine Intervention Society's guidelines for assessing studies on the treatment of pain were applied to a published cost-effectiveness analysis of radiofrequency denervation data from the MINT RCTs.Results: Application of evidence-based medicine principles reveals the MINT RCTs’ major deficiencies in patient selection, diagnostic paradigm, radiofrequency neurotomy technique, co-interventions, outcome measurement, power analysis study sample characteristics, data analysis, and loss to follow-up; which marginalizes the generalizability and conclusions of the cost-effectiveness analysis.Conclusions: The cost analysis performed in “Cost-Effectiveness of Radiofrequency Denervation for Patients With Chronic Low Back Pain: The MINT Randomized Clinical Trials” is based on the MINT RCTs results. The MINT RCTs significant metholodological design flaws, lead to issues in validty for the subsequent cost-effectiveness analysis. Application of the cost-effective analysis to patient care paradigms should be limited given the concerns with validity.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- Chronic Low Back Pain
- Cost Effectiveness
- Evidence-Based Medicine
- Facet Joint
- Radiofrequency Neurotomy
- Sacroiliac Joint
- Zygapophysial Joint
Publication and Content Type
- vet (subject category)
- art (subject category)
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Ehsanian, Reza
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Malone, Daniel C ...
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Hambraeus, Johan
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Monteiro, Pedro ...
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Hodde, Michael
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Lee, David
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McKenna, Michael
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Wahezi, Sayed E.
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McCormick, Zacha ...
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Duszynski, Belin ...
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Cheng, David S.
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- MEDICAL AND HEALTH SCIENCES
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Interventional P ...
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Umeå University