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Searching for genetical cancer risks using a database of familial cancer : part I
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- Eklund, Johan (author)
- Umeå universitet,Institutionen för matematik och matematisk statistik
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(creator_code:org_t)
- Umeå : Umeå universitet, 1999
- English 19 s.
- Related links:
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https://urn.kb.se/re...
Abstract
Subject headings
Close
- A method to estimate cancer risks, when a recessive genetic defect is assumed to influence the risk to develop cancer, is presented. The proportion of the recessive defect is also estimated. The method uses cancer diagnosis data from a large sample of biological families. A family is here parents and two children. The information used is the frequencies of cancer diagnoses among siblings. Estimations are performed with the method of moments. The work is methodological, meaning that no specific type of cancer is considered.
Subject headings
- NATURVETENSKAP -- Matematik -- Sannolikhetsteori och statistik (hsv//swe)
- NATURAL SCIENCES -- Mathematics -- Probability Theory and Statistics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- familial cancer
- genetical cancer risk
- recessive genetic defect
- population frequency
- minimum chi-square test
- method of moments
Publication and Content Type
- vet (subject category)
- rap (subject category)
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