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- Eklund, JohanUmeå universitet,Institutionen för matematik och matematisk statistik (author)
Searching for genetical cancer risks using a database of familial cancer : part I
- BookEnglish1999
Publisher, publication year, extent ...
- Umeå :Umeå universitet,1999
- 19 s.
- printrdacarrier
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- LIBRIS-ID:oai:DiVA.org:umu-25134
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-25134URI
Supplementary language notes
- Language:English
- Summary in:English
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- A method to estimate cancer risks, when a recessive genetic defect is assumed to influence the risk to develop cancer, is presented. The proportion of the recessive defect is also estimated. The method uses cancer diagnosis data from a large sample of biological families. A family is here parents and two children. The information used is the frequencies of cancer diagnoses among siblings. Estimations are performed with the method of moments. The work is methodological, meaning that no specific type of cancer is considered.
Subject headings and genre
- NATURVETENSKAP Matematik Sannolikhetsteori och statistik hsv//swe
- NATURAL SCIENCES Mathematics Probability Theory and Statistics hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
- familial cancer
- genetical cancer risk
- recessive genetic defect
- population frequency
- minimum chi-square test
- method of moments
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- Umeå universitetInstitutionen för matematik och matematisk statistik (creator_code:org_t)
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