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Regioselective Halo...
Regioselective Halogenations and Subsequent Suzuki-Miyaura Coupling onto Bicyclic 2-Pyridones
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- Bengtsson, Christoffer (author)
- Umeå universitet,Kemiska institutionen
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- Almqvist, Fredrik (author)
- Umeå universitet,Kemiska institutionen
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(creator_code:org_t)
- 2009-12-21
- 2010
- English.
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In: The Journal of organic chemistry. - : American Chemical Society. - 1520-6904 .- 0022-3263. ; 75:3, s. 972-5
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- A selective synthesis of 6-bromo-8-iodo dihydro thiazolo ring-fused 2-pyridones is described. These halogenated 2-pyridones are selectively arylated by sequential Suzuki-Miyaura couplings. This approach can advantageously be used to synthesize focused libraries of substituted ring-fused 2-pyridones, a class of compounds with novel antibacterial properties.
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- ref (subject category)
- art (subject category)
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