Search: onr:"swepub:oai:DiVA.org:umu-33270" >
Metabolic syndrome ...
Metabolic syndrome and endometrial carcinoma
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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2010-03-10
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Oxford University Press (OUP),2010
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:umu-33270
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33270URI
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https://doi.org/10.1093/aje/kwq006DOI
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https://lup.lub.lu.se/record/1619566URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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The authors examined the association between the metabolic syndrome and risk of incident endometrial and fatal uterine corpus cancer within a large prospective cohort study. Approximately 290,000 women from Austria, Norway, and Sweden were enrolled during 1974-2005, with measurements of height, weight, systolic and diastolic blood pressure, and circulating levels of glucose, total cholesterol, and triglycerides. Relative risks were estimated using Cox proportional hazards regression. The metabolic syndrome was assessed as a composite z score, as the standardized sum of z scores for body mass index, blood pressure, glucose, cholesterol, and triglycerides. A total of 917 endometrial carcinomas and 129 fatal cancers were identified. Increased risks of incident endometrial carcinoma and fatal uterine corpus cancer were seen for the metabolic syndrome factors combined, as well as for individual factors (except for cholesterol). The relative risk of endometrial carcinoma for the metabolic syndrome was 1.37 (95% confidence interval: 1.28, 1.46) per 1-unit increment of z score. The positive associations between metabolic syndrome factors (both individually and combined) and endometrial carcinoma were confined to the heaviest women. The association between the metabolic syndrome and endometrial carcinoma risk seems to go beyond the risk conferred by obesity alone, particularly in women with a high body mass index.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Stocks, TanjaUmeå University,Umeå universitet,Urologi och andrologi(Swepub:lu)med-tss
(author)
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Lukanova, Annekatrin
(author)
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Tretli, Steinar
(author)
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Selmer, Randi
(author)
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Manjer, JonasLund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups(Swepub:lu)smi-jma
(author)
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Rapp, Kilian
(author)
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Ulmer, Hanno
(author)
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Almquist, MartinLund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups(Swepub:lu)kir-mal
(author)
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Concin, Hans
(author)
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Hallmans, GöranUmeå universitet,Institutionen för folkhälsa och klinisk medicin,Näringsforskning(Swepub:umu)goha0001
(author)
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Jonsson, HåkanUmeå universitet,Onkologi(Swepub:umu)hojo0001
(author)
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Stattin, PärUmeå universitet,Urologi och andrologi(Swepub:umu)past0003
(author)
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Engeland, Anders
(author)
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Umeå universitetUrologi och andrologi
(creator_code:org_t)
Related titles
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In:American Journal of Epidemiology: Oxford University Press (OUP)171:8, s. 892-9020002-92621476-6256
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- By the author/editor
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Bjørge, Tone
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Stocks, Tanja
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Lukanova, Anneka ...
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Tretli, Steinar
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Selmer, Randi
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Manjer, Jonas
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Rapp, Kilian
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Ulmer, Hanno
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Almquist, Martin
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Concin, Hans
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Hallmans, Göran
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Jonsson, Håkan
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Stattin, Pär
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Engeland, Anders
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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Umeå University
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Lund University