onr:"swepub:oai:DiVA.org:umu-34864"
Search: onr:"swepub:oai:DiVA.org:umu-34864" > Brain ventricular s...
- 1 of 1
- Previous record
- Next record
- To hitlist
Brain ventricular size in healthy elderly: comparison between evans index and volume measurement.
-
- Ambarki, Khalid (author)
- Umeå universitet,Radiofysik,Umeå universitet, Radiofysik, Sweden
-
- Israelsson, Hanna (author)
- Umeå universitet,Neurologi,Umeå universitet, Neurologi, Sweden
-
- Wåhlin, Anders (author)
- Umeå universitet,Radiofysik,Umeå universitet, Radiofysik, Sweden
- show more...
- show less...
- (creator_code:org_t)
- Lippincott Williams & Wilkins, 2010
- 2010
- English.
- In: Neurosurgery. - : Lippincott Williams & Wilkins. - 0148-396X .- 1524-4040. ; 67:1, s. 94-99
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- BACKGROUND: A precise definition of ventricular enlargement is important in the diagnosis of hydrocephalus as well as in assessing central atrophy. The Evans index (EI), a linear ratio between the maximal frontal horn width and the cranium diameter, has been extensively used as an indirect marker of ventricular volume (VV). With modern imaging techniques, brain volume can be directly measured. OBJECTIVE: To determine reference values of intracranial volumes in healthy elderly individuals and to correlate volumes with the EI. METHODS: Magnetic resonance imaging (3 T) was performed in 46 healthy white elderly subjects (mean age +/- standard deviation, 71 +/- 6 years) and in 20 patients (74 +/- 7 years) with large ventricles according to visual inspection. VV, relative VV (RVV), and EI were assessed. Ventricular dilation was defined using VV and EI by a value above the 95th percentile range for healthy elderly individuals. RESULTS: In healthy elderly subjects, we found VV = 37 +/- 18 mL, RVV = 2.47 +/- 1.17%, and EI = 0.281 +/- 0.027. Including the patients, there was a strong correlation between EI and VV (R = 0.94) as well as between EI and RVV (R = 0.95). However, because of a wide 95% prediction interval (VV: +/-45 mL; RVV: +/- 2.54%), EI did not give a sufficiently good estimate of VV and RVV. CONCLUSION: VV (or RVV) and the EI reflect different properties. The exclusive use of EI in clinical studies as a marker of enlarged ventricles should be questioned. We suggest that the definition of dilated ventricles in white elderly individuals be defined as VV >77 mL or RVV >4.96 %. Future studies should compare intracranial volumes with clinical characteristics and prognosis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
Keyword
- Aged
- brain ventricular volume and healthy elderly
- cerebrospinal fluid
- cerebral ventricles
- hydrocephalus
- volumetric magnetic resonance imaging
- MEDICINE
- MEDICIN
Publication and Content Type
- ref (subject category)
- art (subject category)
- 1 of 1
- Previous record
- Next record
- To hitlist
Find more in SwePub
- By the author/editor
- Ambarki, Khalid
- Israelsson, Hann ...
- Wåhlin, Anders
- Birgander, Richa ...
- Eklund, Anders
- Malm, Jan
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Clinical Laborat ...
- Articles in the publication
- Neurosurgery
- By the university
- Umeå University
- Linköping University
Search outside SwePub
- Extend your search to:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - National Library Systems
- LIBRIS.kb.se
