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Intestinal flora in...
Intestinal flora in very low-birth weight infants
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- Björkström, Markus V (author)
- Umeå universitet,Pediatrik
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Hall, Lina (author)
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- Söderlund, Stina (author)
- Umeå universitet,Pediatrik
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- Håkansson, Eva Grahn (author)
- Umeå universitet,Klinisk bakteriologi
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- Håkansson, Stellan (author)
- Umeå universitet,Pediatrik
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- Domellöf, Magnus (author)
- Umeå universitet,Pediatrik
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(creator_code:org_t)
- Wiley, 2009
- 2009
- English.
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In: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 98:11, s. 1762-1767
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Subject headings
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- AIM: To study the early faecal microbiota in very low-birth weight infants (VLBW, <1500 g), possible associations between faecal microbiota and faecal calprotectin (f-calprotectin) and to describe the faecal microbiota in cases with necrotizing enterocolitis (NEC) before diagnosis. METHODS: Stool samples from the first weeks of life were analysed in 48 VLBW infants. Bacterial cultures were performed and f-calprotectin concentrations were measured. In three NEC cases, cultures were performed on stool samples obtained before diagnosis. RESULTS: Bifidobacteria and lactobacilli were often identified in the first stool sample, 55% and 71% of cases, respectively within the first week of life. A positive correlation between lactic acid bacteria (LAB) and volume of enteral feed was found. Other bacteria often identified were Escherichia coli, Enterococcus and Staphyloccus sp. F-calprotectin was not associated with any bacterial species. All NEC cases had an early colonization of LAB. Prior to onset of disease, all cases had a high colonization of non-E. coli Gram-negative species. CONCLUSION: In contrast to the previous studies in VLBW infants, we found an early colonization with LAB. We speculate that this may be due to early feeding of non-pasteurized breast milk.
Keyword
- feacal calprotectin
- infant
- intestinal flora
- ecrotizing enterocolitis
- very low-birth weight
Publication and Content Type
- ref (subject category)
- art (subject category)
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