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Unaltered [3H]GBR-1...
Unaltered [3H]GBR-12935 binding after chronic treatment with dopamine active drugs.
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- Allard, Per (author)
- Umeå universitet,Psykiatri
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Eriksson, K (author)
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Ross, S B (author)
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Marcusson, J O (author)
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(creator_code:org_t)
- 1990
- 1990
- English.
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In: Psychopharmacology. - 0033-3158 .- 1432-2072. ; 102:3, s. 291-4
- Related links:
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https://urn.kb.se/re...
Abstract
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- Rats were injected intraperitoneally with haloperidol 0.5 mg/kg, raclopride 1 mg/kg, bromocriptine 2.5 mg/kg, d-amphetamine 2.5 mg/kg, or cocaine 10 mg/kg twice daily for 21 days. The animals were sacrificed 72 h after last injection. Control rats were injected with saline, following the same schedule. The radioligand [3H]GBR-12935 was used as a presynaptic marker for dopamine neurites. There were no significant differences in [3H]GBR-12935 binding to striatum between drug-treated rats and controls.
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- ref (subject category)
- art (subject category)
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