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Towards quorum-quenching catalytic antibodies
- Kapadnis, Prashant B (author)
- Hall, Evan (author)
-
- Ramstedt, Madeleine (author)
- Department of Chemistry, University of Cambridge
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- Galloway, Warren R J D (author)
- Welch, Martin (author)
- Spring, David R (author)
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- (creator_code:org_t)
- RSC Publishing, 2009
- 2009
- English.
- In: Chemical Communications. - : RSC Publishing. - 1359-7345 .- 1364-548X. ; :5, s. 538-540
- Journal article (peer-reviewed)
Abstract
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- The development of a novel method to attenuate bacterial virulence is reported, which is based upon the use of designed transition-state analogues to select human catalytic antibodies capable of degrading bacterial quorum-sensing molecules.
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