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Does abnormal insulin action or insulin secretion explain the increase in prevalence of impaired glucose metabolism with age in populations of different ethnicities?

Ning, F (author): Department of Public Health, University of Helsinki, Helsinki, Finland

Qiao, Q (author): Department of Public Health, University of Helsinki, Helsinki, Finland

Tuomilehto, J (author): Department of Public Health, University of Helsinki, Helsinki, Finland

Hammar, N (author): Karolinska Institutet

Ho, S Y (author): Department of Community Medicine, University of Hong Kong, Hong Kong SAR, China

Söderberg, Stefan (author): Umeå universitet,Medicin

Zimmet, P Z (author): Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

Shaw, J E (author): Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

Nakagami, T (author): Diabetes Center, Tokyo Women's Medical University School of Medicine, Tokyo, Japan

Mohan, V (author): Madras Diabetes Research Foundation, Dr Mohan's Diabetes Specialities Centre, Chennai, India

Ramachandran, A (author): India Diabetes Research Foundation, Dr A. Ramachandran's Diabetes Hospitals, Chennai, India

Lam, T H (author): Department of Community Medicine, University of Hong Kong, Hong Kong SAR, China

Andersson, S W (author): Department of Clinical Nutrition, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden

Janus, E D (author): Department of Community Medicine, University of Hong Kong, Hong Kong SAR, China

Boyko, E J (author): Department of Medicine, University of Washington, Seattle, WA, USA

Fujimoto, W Y (author): Department of Medicine, University of Washington, Seattle, WA, USA

Pang, Z C (author): Qingdao Centers for Disease Control and Prevention, Qingdao, China

(creator_code:org_t)

2010-04-15
2010
English.
In: Diabetes/Metabolism Research Reviews. - : Wiley. - 1520-7552 .- 1520-7560. ; 26:4, s. 245-253

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The age-related increase in glucose intolerance may not be fully explained by the defect in HOMA-IR and HOMA-B. As HOMA-IR and HOMA-B are only surrogate measures of insulin sensitivity and insulin secretion, the results need to be further investigated.

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By the author/editor: Ning, F; Qiao, Q; Tuomilehto, J; Hammar, N; Ho, S Y; Söderberg, Stefa ...; show more...; Zimmet, P Z; Shaw, J E; Nakagami, T; Mohan, V; Ramachandran, A; Lam, T H; Andersson, S W; Janus, E D; Boyko, E J; Fujimoto, W Y; Pang, Z C; show less...

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By the university: Umeå University; Karolinska Institutet

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