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Assessing the value of CAN-gene mutations using MALDI-TOF MS

Kohler, Corina (author)
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland
Tavelin, Björn (author)
Umeå universitet,Onkologi
Fan, Alex Xiu-Cheng (author)
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland
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Radpour, Ramin (author)
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland
Barekati, Zeinab (author)
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland
Levi, Fabio (author)
Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
Zhong, Xiao Yan (author)
Laboratory for Gynecological Oncology, Women’s Hospital/Department Research, Department of Biomedicine, University of Basel, Basel, Switzerland
Lenner, Per (author)
Umeå universitet,Onkologi
Toniolo, Paolo (author)
Institute of Social and Preventive Medicine (IUMSP), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland,Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA
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 (creator_code:org_t)
2011-06-21
2011
English.
In: Journal of Cancer Research and Clinical Oncology. - : Springer Science and Business Media LLC. - 0171-5216 .- 1432-1335. ; 137:8, s. 1239-1244
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Sjöblom et al./Wood et al. already showed that the vast majority of CAN-genes are mutated at very low frequency. Due to the fact that we only found one mutation in our cohort, we therefore assume that at the selected loci, mutations might be low-frequency events and therefore, more rarely detectable. However, further evaluation of the CAN-gene mutations in larger cohorts should be the aim of further studies.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

Breast cancer
CAN-genes
MALDI-TOF MS
Multiplex assay
onkologi
Oncology

Publication and Content Type

ref (subject category)
art (subject category)

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