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Asthma in adults an...
Asthma in adults and its association with chronic rhinosinusitis : the GA(2) LEN survey in Europe
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Jarvis, D (author)
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Newson, R (author)
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- Lötvall, Jan, 1956 (author)
- Gothenburg University,Göteborgs universitet,Krefting Research Centre
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Hastan, D (author)
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Tomassen, P (author)
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Keil, T (author)
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Gjomarkaj, M (author)
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- Forsberg, Bertil (author)
- Umeå universitet,Yrkes- och miljömedicin
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- Gunnbjörnsdottir, Maria (author)
- Uppsala universitet,Lungmedicin och allergologi
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Minov, J (author)
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Brozek, G (author)
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- Dahlen, SE (author)
- Karolinska Institutet
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Toskala, E (author)
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Kowalski, ML (author)
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Olze, H (author)
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Howarth, P (author)
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Krämer, U (author)
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Baelum, J (author)
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Loureiro, C (author)
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Kasper, L (author)
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Bousquet, PJ (author)
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Bousquet, J (author)
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- Bachert, C (author)
- Karolinska Institutet
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Fokkens, W (author)
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Burney, P (author)
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(creator_code:org_t)
- 2011-11-04
- 2012
- English.
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In: Allergy. European Journal of Allergy and Clinical Immunology. - : Wiley. - 0105-4538 .- 1398-9995. ; 67:1, s. 91-98
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https://doi.org/10.1...
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Abstract
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- Background: The prevalence of asthma and its association with chronic rhinosinusitis (CRS) have not been widely studied in population-based epidemiological surveys. Methods: The Global Allergy and Asthma Network of Excellence (GA2LEN) conducted a postal questionnaire in representative samples of adults living in Europe to assess the presence of asthma and CRS defined by the European Position Paper on Rhinosinusitis and Nasal Polyps. The prevalence of self-reported current asthma by age group was determined. The association of asthma with CRS in each participating centre was assessed using logistic regression analyses, controlling for age, sex and smoking, and the effect estimates were combined using standard methods of meta-analysis. Results: Over 52 000 adults aged 18–75 years and living in 19 centres in 12 countries took part. In most centres, and overall, the reported prevalence of asthma was lower in older adults (adjusted OR for 65–74 years compared with 15–24 years: 0.72; 95% CI: 0.63–0.81). In all centres, there was a strong association of asthma with CRS (adjusted OR: 3.47; 95% CI: 3.20–3.76) at all ages. The association with asthma was stronger in those reporting both CRS and allergic rhinitis (adjusted OR: 11.85; 95% CI: 10.57–13.17). CRS in the absence of nasal allergies was positively associated with late-onset asthma. Conclusion: Geographical variation in the prevalence of self-reported asthma was observed across Europe, but overall, self-reported asthma was more common in young adults, women and smokers. In all age groups, men and women, and irrespective of smoking behaviour, asthma was also associated with CRS.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Immunologi inom det medicinska området (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Immunology in the medical area (hsv//eng)
Keyword
- asthma
- chronic rhinosinusitis
- epidemiology
- GA2LEN
Publication and Content Type
- ref (subject category)
- art (subject category)
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To the university's database
- By the author/editor
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Jarvis, D
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Newson, R
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Lötvall, Jan, 19 ...
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Hastan, D
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Tomassen, P
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Keil, T
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show more...
-
Gjomarkaj, M
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Forsberg, Bertil
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Gunnbjörnsdottir ...
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Minov, J
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Brozek, G
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Dahlen, SE
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Toskala, E
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Kowalski, ML
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Olze, H
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Howarth, P
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Krämer, U
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Baelum, J
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Loureiro, C
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Kasper, L
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Bousquet, PJ
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Bousquet, J
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Bachert, C
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Fokkens, W
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Burney, P
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Occupational Hea ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Immunology in th ...
- Articles in the publication
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Allergy. Europea ...
- By the university
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Umeå University
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Uppsala University
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Karolinska Institutet
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University of Gothenburg